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Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis.
Thomas, Michael G; De Rycker, Manu; Ajakane, Myriam; Crouch, Sabrinia D; Campbell, Lorna; Daugan, Alain; Fra, Gloria; Guerrero, César; Mackenzie, Claire J; MacLean, Lorna; Manthri, Sujatha; Martin, Franck; Norval, Suzanne; Osuna-Cabello, Maria; Riley, Jennifer; Shishikura, Yoko; Miguel-Siles, Juan; Simeons, Frederick R C; Stojanovski, Laste; Thomas, John; Thompson, Stephen; Velasco, Raul F; Fiandor, Jose M; Wyatt, Paul G; Read, Kevin D; Gilbert, Ian H; Miles, Timothy J.
Afiliación
  • Thomas MG; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • De Rycker M; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Ajakane M; Centre de Recherche , GlaxoSmithKline , Les Ulis, 25,27 Avenue du Quebec , 91140 Villebon sur Yvette , France.
  • Crouch SD; Global Health R&D , GlaxoSmithKline , Calle Severo Ochoa, 2, 28760 Tres Cantos , Madrid , Spain . Email: tim.j.miles@gsk.com.
  • Campbell L; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Daugan A; Centre de Recherche , GlaxoSmithKline , Les Ulis, 25,27 Avenue du Quebec , 91140 Villebon sur Yvette , France.
  • Fra G; GalChimia S.A. , Cebreiro s/n, 15823, O Pino , A Coruña , Spain.
  • Guerrero C; GalChimia S.A. , Cebreiro s/n, 15823, O Pino , A Coruña , Spain.
  • Mackenzie CJ; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • MacLean L; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Manthri S; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Martin F; Centre de Recherche , GlaxoSmithKline , Les Ulis, 25,27 Avenue du Quebec , 91140 Villebon sur Yvette , France.
  • Norval S; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Osuna-Cabello M; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Riley J; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Shishikura Y; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Miguel-Siles J; Global Health R&D , GlaxoSmithKline , Calle Severo Ochoa, 2, 28760 Tres Cantos , Madrid , Spain . Email: tim.j.miles@gsk.com.
  • Simeons FRC; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Stojanovski L; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Thomas J; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Thompson S; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Velasco RF; GalChimia S.A. , Cebreiro s/n, 15823, O Pino , A Coruña , Spain.
  • Fiandor JM; Global Health R&D , GlaxoSmithKline , Calle Severo Ochoa, 2, 28760 Tres Cantos , Madrid , Spain . Email: tim.j.miles@gsk.com.
  • Wyatt PG; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Read KD; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Gilbert IH; Drug Discovery Unit , Wellcome Centre for Anti-Infectives Research , Division of Biological Chemistry and Drug Discovery , School of Life Sciences , University of Dundee , Dundee DD1 5EH , UK . Email: I.H.Gilbert@dundee.ac.uk.
  • Miles TJ; Global Health R&D , GlaxoSmithKline , Calle Severo Ochoa, 2, 28760 Tres Cantos , Madrid , Spain . Email: tim.j.miles@gsk.com.
RSC Med Chem ; 11(10): 1168-1177, 2020 Oct 01.
Article en En | MEDLINE | ID: mdl-33479621

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: RSC Med Chem Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: RSC Med Chem Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido