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3D scaffold-free microlivers with drug metabolic function generated by lineage-reprogrammed hepatocytes from human fibroblasts.
Lu, Zuyan; Priya Rajan, Shiny Amala; Song, Qianqian; Zhao, Yu; Wan, Meimei; Aleman, Julio; Skardal, Aleksander; Bishop, Colin; Atala, Anthony; Lu, Baisong.
Afiliación
  • Lu Z; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
  • Priya Rajan SA; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
  • Song Q; Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.
  • Zhao Y; Jiangsu Healthy Life Innovation Medical Technology Co, Ltd., Wuxi, Jiangsu Province, China.
  • Wan M; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
  • Aleman J; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
  • Skardal A; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, USA; Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA.
  • Bishop C; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
  • Atala A; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, USA. Electronic address: aatala@wakehealth.edu.
  • Lu B; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, USA. Electronic address: blu@wakehealth.edu.
Biomaterials ; 269: 120668, 2021 02.
Article en En | MEDLINE | ID: mdl-33461059
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preparaciones Farmacéuticas / Hepatocitos Tipo de estudio: Prognostic_studies Límite: Adult / Humans Idioma: En Revista: Biomaterials Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preparaciones Farmacéuticas / Hepatocitos Tipo de estudio: Prognostic_studies Límite: Adult / Humans Idioma: En Revista: Biomaterials Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos