Effect of preeclampsia on carboxyhemoglobin levels: a mechanism for a decrease in P50.

Kambam, J R; Entman, S; Mouton, S; Smith, B E

Kambam, J R; Entman, S; Mouton, S; Smith, B E.

Afiliación

Kambam JR; Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.

Anesthesiology ; 68(3): 433-4, 1988 Mar.

Article en En | MEDLINE | ID: mdl-3344999

RESUMEN

COHb levels were measured in 15 preeclamptic pregnant women and 15 normal pregnant women to investigate the cause for the decrease in P50 associated with preeclampsia. The authors also included six normal and six preeclamptic pregnant patients from the above groups in the determination of P50. Measurements of COHb levels were performed in a Radiometer OSM2 Hemoximeter. Determination of P50 was done using an IL 237 Tonometer, a Radiometer, OSM2 Hemoximeter, and a Corning 168 pH/Blood Gas Analyzer. Preeclamptic pregnant patients had a mean COHb level of 2.8%, whereas normal pregnant women had a mean COHb level of 0.7% (P less than 0.001). Preeclamptic patients also had a significantly lower (24.4 mmHg) P50 than normal pregnant women (P50 = 30.1 mmHg) (P less than 0.001). The authors conclude that a significant elevation of COHb in preeclamptic pregnant women is partly responsible for a significant decrease in P50 seen in preeclampsia.

Asunto(s)

Carboxihemoglobina/análisis; Oxihemoglobinas/metabolismo; Preeclampsia/sangre; Femenino; Humanos; Embarazo

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preeclampsia / Carboxihemoglobina / Oxihemoglobinas Límite: Female / Humans / Pregnancy Idioma: En Revista: Anesthesiology Año: 1988 Tipo del documento: Article Pais de publicación: Estados Unidos

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links