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Huge ovarian cyst in a neonate with classical 21-hydroxylase deficiency.
Abdelmeguid, Yasmine; Yakout, Nada; Oshiba, Ahmed; Zain, Mostafa; Kotb, Mostafa.
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  • Abdelmeguid Y; Department of Pediatric Endocrinology, Alexandria Faculty of Medicine, Alexandria, Egypt.
  • Yakout N; Department of Pathology, Alexandria Faculty of Medicine, Alexandria, Egypt.
  • Oshiba A; Department of Pediatric Surgery, Alexandria Faculty of Medicine, Alexandria, Egypt.
  • Zain M; Department of Pediatric Surgery, Alexandria Faculty of Medicine, Alexandria, Egypt.
  • Kotb M; Department of Pediatric Surgery, Alexandria Faculty of Medicine, Alexandria, Egypt.
Clin Pediatr Endocrinol ; 30(1): 57-60, 2021.
Article en En | MEDLINE | ID: mdl-33446954
Congenital adrenal hyperplasia is the most common cause of ambiguous genitalia worldwide, with an incidence of 1 in 15,000 live births. The most frequently-occurring subtype, 21-hydroxylase deficiency, results in diminished production of aldosterone and cortisol as well as increased androgen secretion. Previous studies have reported a relationship between ovarian cyst formation and adrenal androgen excess; nevertheless, neonatal large ovarian cysts have rarely been reported in newborns with congenital adrenal hyperplasia. Herein, we present the unique case of a neonate with classical 21-hydroxylase deficiency who underwent surgery for a huge unilateral solitary ovarian follicular cyst on the seventh postnatal day. Possible mechanisms by which androgen excess may cause ovarian cyst formation are also discussed.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Pediatr Endocrinol Año: 2021 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Japón
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Pediatr Endocrinol Año: 2021 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Japón