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Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy.
Tajan, Mylène; Hennequart, Marc; Cheung, Eric C; Zani, Fabio; Hock, Andreas K; Legrave, Nathalie; Maddocks, Oliver D K; Ridgway, Rachel A; Athineos, Dimitris; Suárez-Bonnet, Alejandro; Ludwig, Robert L; Novellasdemunt, Laura; Angelis, Nikolaos; Li, Vivian S W; Vlachogiannis, Georgios; Valeri, Nicola; Mainolfi, Nello; Suri, Vipin; Friedman, Adam; Manfredi, Mark; Blyth, Karen; Sansom, Owen J; Vousden, Karen H.
Afiliación
  • Tajan M; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Hennequart M; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Cheung EC; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Zani F; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Hock AK; Cancer Research UK Beatson Institute, Switchback Road, Glasgow, G61 1BD, UK.
  • Legrave N; Mechanistic Biology and Profiling, Discovery Sciences, R&D, AstraZeneca, Cambridge, UK.
  • Maddocks ODK; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Ridgway RA; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, G61 1QH, UK.
  • Athineos D; Cancer Research UK Beatson Institute, Switchback Road, Glasgow, G61 1BD, UK.
  • Suárez-Bonnet A; Cancer Research UK Beatson Institute, Switchback Road, Glasgow, G61 1BD, UK.
  • Ludwig RL; The Royal Veterinary College, Hawkshead Lane, Harfield, Herts, AL9 7TA, UK.
  • Novellasdemunt L; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Angelis N; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Li VSW; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Vlachogiannis G; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Valeri N; Gastrointestinal Cancer Biology and Genomics Team, Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.
  • Mainolfi N; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK.
  • Suri V; Gastrointestinal Cancer Biology and Genomics Team, Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.
  • Friedman A; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK.
  • Manfredi M; Department of Medicine, The Royal Marsden NHS Foundation Trust, London, UK.
  • Blyth K; Raze Therapeutics, Inc., Cambridge, MA, USA.
  • Sansom OJ; Raze Therapeutics, Inc., Cambridge, MA, USA.
  • Vousden KH; Raze Therapeutics, Inc., Cambridge, MA, USA.
Nat Commun ; 12(1): 366, 2021 01 14.
Article en En | MEDLINE | ID: mdl-33446657
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Serina / Glicina / Neoplasias Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Serina / Glicina / Neoplasias Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido