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Toward improved human health: efficacy of dietary selenium on immunity at the cellular level.
Xia, Xiaojing; Zhang, Xiulin; Liu, Mingcheng; Duan, Mingyuan; Zhang, Shanshan; Wei, Xiaobing; Liu, Xingyou.
Afiliación
  • Xia X; College of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, PR China. quick500@163.com.
  • Zhang X; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, Shanxi, PR China.
  • Liu M; College of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, PR China. quick500@163.com.
  • Duan M; College of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, PR China. quick500@163.com.
  • Zhang S; College of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, PR China. quick500@163.com.
  • Wei X; College of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, Henan, PR China. quick500@163.com.
  • Liu X; Xinxiang University, Xinxiang 453003, Henan, PR China. 88983867@qq.com lxingyou@sohu.com.
Food Funct ; 12(3): 976-989, 2021 Feb 15.
Article en En | MEDLINE | ID: mdl-33443499
Selenium, an essential trace element in the body, participates in various biological processes in the form of selenoproteins. In humans, a suitable concentration of selenium is essential for maintaining normal cellular function. Decreased levels of selenoproteins can lead to obstruction of the normal physiological functions of tissues and cells and even death. In addition, the level of selenium in the body affects cellular immunity, humoral immunity, and the balance between type 2 and type 1 helper T cells. Selenium can affect the immune function of the body through the reactive oxygen species (ROS), NF-κB, ferroptosis and NRF2 pathways. This paper reviews the immune effect of selenium on the body and the process of signal transduction and aims to serve as a reference for follow-up studies of immune function and research on the development of new selenium compounds and active targets.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Selenio / Oligoelementos / Dieta / Inmunidad Celular Tipo de estudio: Observational_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Food Funct Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Selenio / Oligoelementos / Dieta / Inmunidad Celular Tipo de estudio: Observational_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Food Funct Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido