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Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
Aschenbrenner, Anna C; Mouktaroudi, Maria; Krämer, Benjamin; Oestreich, Marie; Antonakos, Nikolaos; Nuesch-Germano, Melanie; Gkizeli, Konstantina; Bonaguro, Lorenzo; Reusch, Nico; Baßler, Kevin; Saridaki, Maria; Knoll, Rainer; Pecht, Tal; Kapellos, Theodore S; Doulou, Sarandia; Kröger, Charlotte; Herbert, Miriam; Holsten, Lisa; Horne, Arik; Gemünd, Ioanna D; Rovina, Nikoletta; Agrawal, Shobhit; Dahm, Kilian; van Uelft, Martina; Drews, Anna; Lenkeit, Lena; Bruse, Niklas; Gerretsen, Jelle; Gierlich, Jannik; Becker, Matthias; Händler, Kristian; Kraut, Michael; Theis, Heidi; Mengiste, Simachew; De Domenico, Elena; Schulte-Schrepping, Jonas; Seep, Lea; Raabe, Jan; Hoffmeister, Christoph; ToVinh, Michael; Keitel, Verena; Rieke, Gereon; Talevi, Valentina; Skowasch, Dirk; Aziz, N Ahmad; Pickkers, Peter; van de Veerdonk, Frank L; Netea, Mihai G; Schultze, Joachim L; Kox, Matthijs.
Afiliación
  • Aschenbrenner AC; Systems Medicine, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Mouktaroudi M; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany.
  • Krämer B; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Oestreich M; Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.
  • Antonakos N; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
  • Nuesch-Germano M; Department I of Internal Medicine, University Hospital of Bonn (UKB), Bonn, Germany.
  • Gkizeli K; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Bonaguro L; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
  • Reusch N; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Baßler K; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
  • Saridaki M; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Knoll R; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Pecht T; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Kapellos TS; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
  • Doulou S; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Kröger C; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Herbert M; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Holsten L; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Horne A; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Gemünd ID; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Rovina N; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Agrawal S; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Dahm K; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • van Uelft M; 1st Department of Pulmonary Medicine and Intensive Care Unit, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
  • Drews A; West German Genome Center (WGGC), University of Bonn, Bonn, Germany.
  • Lenkeit L; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Bruse N; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Gerretsen J; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany.
  • Gierlich J; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Becker M; Department of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.
  • Händler K; Department of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.
  • Kraut M; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Theis H; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany.
  • Mengiste S; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany.
  • De Domenico E; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany.
  • Schulte-Schrepping J; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany.
  • Seep L; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Raabe J; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany.
  • Hoffmeister C; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • ToVinh M; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
  • Keitel V; Department I of Internal Medicine, University Hospital of Bonn (UKB), Bonn, Germany.
  • Rieke G; Department I of Internal Medicine, University Hospital of Bonn (UKB), Bonn, Germany.
  • Talevi V; Department I of Internal Medicine, University Hospital of Bonn (UKB), Bonn, Germany.
  • Skowasch D; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Aziz NA; Department I of Internal Medicine, University Hospital of Bonn (UKB), Bonn, Germany.
  • Pickkers P; Population Health Sciences, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • van de Veerdonk FL; Department of Internal Medicine II, Section of Pneumology, University Hospital of Bonn (UKB), Bonn, Germany.
  • Netea MG; Population Health Sciences, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Schultze JL; Department of Neurology, Faculty of Medicine, University of Bonn, Bonn, Germany.
  • Kox M; Department of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.
Genome Med ; 13(1): 7, 2021 01 13.
Article en En | MEDLINE | ID: mdl-33441124

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transcriptoma / COVID-19 / Neutrófilos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Genome Med Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transcriptoma / COVID-19 / Neutrófilos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Genome Med Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido