Capitalizing on Synthetic Lethality of MYC to Treat Cancer in the Digital Age.

Thng, Dexter Kai Hao; Toh, Tan Boon; Chow, Edward Kai-Hua

Thng, Dexter Kai Hao; Toh, Tan Boon; Chow, Edward Kai-Hua.

Afiliación

Thng DKH; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Toh TB; The N.1 Institute for Health, National University of Singapore, Singapore; The Institute for Digital Medicine (WisDM), Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Chow EK; Cancer Science Institute of Singapore, National University of Singapore, Singapore; The N.1 Institute for Health, National University of Singapore, Singapore; The Institute for Digital Medicine (WisDM), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Biomedical Engineering, National University of Singapore, Singapore. Electronic address: csikce@nus

Trends Pharmacol Sci ; 42(3): 166-182, 2021 03.

Article en En | MEDLINE | ID: mdl-33422376

Asunto(s)

Neoplasias; Proteínas Proto-Oncogénicas c-myc; Mutaciones Letales Sintéticas; Humanos; Neoplasias/tratamiento farmacológico; Neoplasias/genética; Oncogenes; Proteínas Proto-Oncogénicas c-myc/genética

Palabras clave

MYC; cancer; computational; drug targets; synthetic lethality

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas c-myc / Mutaciones Letales Sintéticas / Neoplasias Límite: Humans Idioma: En Revista: Trends Pharmacol Sci Año: 2021 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Reino Unido

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