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Identification of a 1-deoxy-D-xylulose-5-phosphate synthase (DXS) mutant with improved crystallographic properties.
Gierse, Robin M; Reddem, Eswar R; Alhayek, Alaa; Baitinger, Dominik; Hamid, Zhoor; Jakobi, Harald; Laber, Bernd; Lange, Gudrun; Hirsch, Anna K H; Groves, Matthew R.
Afiliación
  • Gierse RM; Department for Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E 8.1, 66123, Saarbrücken, Germany; Department of Pharmacy, Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany; Str
  • Reddem ER; Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 7, 9747, AG Groningen, Netherlands; Pharmacy Department, Drug Design Group, University of Groningen, Antonius Deusinglaan 1, 9700, AV Groningen, Netherlands.
  • Alhayek A; Department for Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E 8.1, 66123, Saarbrücken, Germany; Department of Pharmacy, Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany.
  • Baitinger D; Department for Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E 8.1, 66123, Saarbrücken, Germany.
  • Hamid Z; Department for Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E 8.1, 66123, Saarbrücken, Germany; Department of Pharmacy, Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany.
  • Jakobi H; Research & Development Crop Science, Bayer AG, Industriepark Höchst, 65926, Frankfurt, Germany.
  • Laber B; Research & Development Crop Science, Bayer AG, Industriepark Höchst, 65926, Frankfurt, Germany.
  • Lange G; Research & Development Crop Science, Bayer AG, Industriepark Höchst, 65926, Frankfurt, Germany.
  • Hirsch AKH; Department for Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research (HIPS) - Helmholtz Centre for Infection Research (HZI), Campus Building E 8.1, 66123, Saarbrücken, Germany; Department of Pharmacy, Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany; Str
  • Groves MR; Pharmacy Department, Drug Design Group, University of Groningen, Antonius Deusinglaan 1, 9700, AV Groningen, Netherlands. Electronic address: m.r.groves@rug.nl.
Biochem Biophys Res Commun ; 539: 42-47, 2021 02 05.
Article en En | MEDLINE | ID: mdl-33421767
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transferasas / Deinococcus / Escherichia coli / Proteínas Mutantes Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Biochem Biophys Res Commun Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transferasas / Deinococcus / Escherichia coli / Proteínas Mutantes Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Biochem Biophys Res Commun Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos