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Pelvic Organ Prolapse: A Review of In Vitro Testing of Pelvic Support Mechanisms.
Conway, Cassandra K; White, Shelby E; Russell, Rachel; Sentilles, Claire; Clark-Patterson, Gabrielle L; Miller, Kristin S; Desrosiers, Laurephile; Knoepp, Leise R.
Afiliación
  • Conway CK; Department of Biomedical Engineering, Tulane University, New Orleans, LA.
  • White SE; Department of Biomedical Engineering, Tulane University, New Orleans, LA.
  • Russell R; Department of Biomedical Engineering, Tulane University, New Orleans, LA.
  • Sentilles C; Department of Biomedical Engineering, Tulane University, New Orleans, LA.
  • Clark-Patterson GL; Department of Biomedical Engineering, Tulane University, New Orleans, LA.
  • Miller KS; Department of Biomedical Engineering, Tulane University, New Orleans, LA.
  • Desrosiers L; Department of Obstetrics and Gynecology, Division of Female Pelvic Medicine and Reconstructive Surgery, Ochsner Clinic Foundation, New Orleans, LA.
  • Knoepp LR; The University of Queensland Faculty of Medicine, Ochsner Clinical School, New Orleans, LA.
Ochsner J ; 20(4): 410-418, 2020.
Article en En | MEDLINE | ID: mdl-33408579
Background: Pelvic organ prolapse (POP) affects a significant portion of the female population, impacting quality of life and often requiring intervention. The exact cause of prolapse is unknown. Methods: We review some of the current research that focuses on defining the elements involved in POP, with a focus on in vitro testing. Results: Treatment for POP, ranging from physical therapy or pessary use to more invasive surgery, has varying success rates. This variation is, in part, because the pathophysiology of pelvic floor support-and thus dysfunction-is incompletely understood, particularly regarding the structural components and biomechanical properties of tissue. However, researchers are working to identify and quantify the structural and functional dysfunction that may lead to the development of this condition. Conclusion: Given the limited understanding of prolapse development, more research is needed to quantify the microstructure of the pelvic organs and pelvic support structures, with and without prolapse. Identifying biomechanical properties in multiaxial configurations will improve our understanding of pelvic tissue support, as well as our ability to establish predictive models and improve clinical treatment strategies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Aspecto: Patient_preference Idioma: En Revista: Ochsner J Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Aspecto: Patient_preference Idioma: En Revista: Ochsner J Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos