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Platypus and echidna genomes reveal mammalian biology and evolution.
Zhou, Yang; Shearwin-Whyatt, Linda; Li, Jing; Song, Zhenzhen; Hayakawa, Takashi; Stevens, David; Fenelon, Jane C; Peel, Emma; Cheng, Yuanyuan; Pajpach, Filip; Bradley, Natasha; Suzuki, Hikoyu; Nikaido, Masato; Damas, Joana; Daish, Tasman; Perry, Tahlia; Zhu, Zexian; Geng, Yuncong; Rhie, Arang; Sims, Ying; Wood, Jonathan; Haase, Bettina; Mountcastle, Jacquelyn; Fedrigo, Olivier; Li, Qiye; Yang, Huanming; Wang, Jian; Johnston, Stephen D; Phillippy, Adam M; Howe, Kerstin; Jarvis, Erich D; Ryder, Oliver A; Kaessmann, Henrik; Donnelly, Peter; Korlach, Jonas; Lewin, Harris A; Graves, Jennifer; Belov, Katherine; Renfree, Marilyn B; Grutzner, Frank; Zhou, Qi; Zhang, Guojie.
Afiliación
  • Zhou Y; BGI-Shenzhen, Shenzhen, China.
  • Shearwin-Whyatt L; Villum Center for Biodiversity Genomics, Section for Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
  • Li J; School of Biological Sciences, The Environment Institute, The University of Adelaide, Adelaide, South Australia, Australia.
  • Song Z; MOE Laboratory of Biosystems Homeostasis and Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Hayakawa T; BGI-Shenzhen, Shenzhen, China.
  • Stevens D; BGI Education Center, University of Chinese Academy of Sciences, Shenzhen, China.
  • Fenelon JC; Faculty of Environmental Earth Science, Hokkaido University, Sapporo, Japan.
  • Peel E; Japan Monkey Centre, Inuyama, Japan.
  • Cheng Y; School of Biological Sciences, The Environment Institute, The University of Adelaide, Adelaide, South Australia, Australia.
  • Pajpach F; School of BioSciences, The University of Melbourne, Melbourne, Victoria, Australia.
  • Bradley N; School of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.
  • Suzuki H; School of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.
  • Nikaido M; School of Biological Sciences, The Environment Institute, The University of Adelaide, Adelaide, South Australia, Australia.
  • Damas J; School of Biological Sciences, The Environment Institute, The University of Adelaide, Adelaide, South Australia, Australia.
  • Daish T; digzyme Inc, Tokyo, Japan.
  • Perry T; School of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.
  • Zhu Z; The Genome Center, University of California, Davis, CA, USA.
  • Geng Y; School of Biological Sciences, The Environment Institute, The University of Adelaide, Adelaide, South Australia, Australia.
  • Rhie A; School of Biological Sciences, The Environment Institute, The University of Adelaide, Adelaide, South Australia, Australia.
  • Sims Y; MOE Laboratory of Biosystems Homeostasis and Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Wood J; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.
  • Haase B; Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
  • Mountcastle J; Tree of Life Programme, Wellcome Sanger Institute, Cambridge, UK.
  • Fedrigo O; Tree of Life Programme, Wellcome Sanger Institute, Cambridge, UK.
  • Li Q; The Vertebrate Genome Lab, The Rockefeller University, New York, NY, USA.
  • Yang H; The Vertebrate Genome Lab, The Rockefeller University, New York, NY, USA.
  • Wang J; The Vertebrate Genome Lab, The Rockefeller University, New York, NY, USA.
  • Johnston SD; BGI-Shenzhen, Shenzhen, China.
  • Phillippy AM; BGI-Shenzhen, Shenzhen, China.
  • Howe K; James D. Watson Institute of Genome Sciences, Hangzhou, China.
  • Jarvis ED; University of the Chinese Academy of Sciences, Beijing, China.
  • Ryder OA; Guangdong Provincial Academician Workstation of BGI Synthetic Genomics, BGI-Shenzhen, Shenzhen, China.
  • Kaessmann H; BGI-Shenzhen, Shenzhen, China.
  • Donnelly P; James D. Watson Institute of Genome Sciences, Hangzhou, China.
  • Korlach J; School of Agriculture and Food Sciences, The University of Queensland, Gatton, Queensland, Australia.
  • Lewin HA; Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
  • Graves J; Tree of Life Programme, Wellcome Sanger Institute, Cambridge, UK.
  • Belov K; Laboratory of Neurogenetics of Language, The Rockefeller University, New York, NY, USA.
  • Renfree MB; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
  • Grutzner F; San Diego Zoo Global, Escondido, CA, USA.
  • Zhou Q; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.
  • Zhang G; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Nature ; 592(7856): 756-762, 2021 04.
Article en En | MEDLINE | ID: mdl-33408411
Egg-laying mammals (monotremes) are the only extant mammalian outgroup to therians (marsupial and eutherian animals) and provide key insights into mammalian evolution1,2. Here we generate and analyse reference genomes of the platypus (Ornithorhynchus anatinus) and echidna (Tachyglossus aculeatus), which represent the only two extant monotreme lineages. The nearly complete platypus genome assembly has anchored almost the entire genome onto chromosomes, markedly improving the genome continuity and gene annotation. Together with our echidna sequence, the genomes of the two species allow us to detect the ancestral and lineage-specific genomic changes that shape both monotreme and mammalian evolution. We provide evidence that the monotreme sex chromosome complex originated from an ancestral chromosome ring configuration. The formation of such a unique chromosome complex may have been facilitated by the unusually extensive interactions between the multi-X and multi-Y chromosomes that are shared by the autosomal homologues in humans. Further comparative genomic analyses unravel marked differences between monotremes and therians in haptoglobin genes, lactation genes and chemosensory receptor genes for smell and taste that underlie the ecological adaptation of monotremes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ornitorrinco / Genoma / Tachyglossidae / Evolución Biológica Límite: Animals Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ornitorrinco / Genoma / Tachyglossidae / Evolución Biológica Límite: Animals Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido