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Seeking an Initial-Weight-Independent Metric in a Mediterranean Cohort of Gastric Bypass Patients: the %AWL Revisited.
Beisani, Marc; Sabench Pereferrer, Fàtima; Vilallonga, Ramón; González López, Óscar; Molina López, Alicia; Del Castillo Dejardin, Daniel; García Ruiz de Gordejuela, Amador; Fort López-Barajas, José Manuel; Armengol Carrasco, Manel.
Afiliación
  • Beisani M; General and Digestive Surgery Department, Vall d'Hebron University Campus, Autonomous University of Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.
  • Sabench Pereferrer F; General and Digestive Surgery Department, Pere Virgili Health's Institute, Faculty of Medicine, University Hospital of Sant Joan de Reus, Avinguda del Doctor Josep Laporte, 2, 43204, Reus, Spain.
  • Vilallonga R; General and Digestive Surgery Department, Vall d'Hebron University Campus, Autonomous University of Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.
  • González López Ó; General and Digestive Surgery Department, Vall d'Hebron University Campus, Autonomous University of Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain. 40667ogl@gmail.com.
  • Molina López A; General and Digestive Surgery Department, Pere Virgili Health's Institute, Faculty of Medicine, University Hospital of Sant Joan de Reus, Avinguda del Doctor Josep Laporte, 2, 43204, Reus, Spain.
  • Del Castillo Dejardin D; General and Digestive Surgery Department, Pere Virgili Health's Institute, Faculty of Medicine, University Hospital of Sant Joan de Reus, Avinguda del Doctor Josep Laporte, 2, 43204, Reus, Spain.
  • García Ruiz de Gordejuela A; General and Digestive Surgery Department, Vall d'Hebron University Campus, Autonomous University of Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.
  • Fort López-Barajas JM; General and Digestive Surgery Department, Vall d'Hebron University Campus, Autonomous University of Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.
  • Armengol Carrasco M; General and Digestive Surgery Department, Vall d'Hebron University Campus, Autonomous University of Barcelona, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.
Obes Surg ; 31(4): 1524-1532, 2021 Apr.
Article en En | MEDLINE | ID: mdl-33398625
BACKGROUND: Most relative weight-loss metrics follow the formula "Weight loss(%) = 100 · (Initial BMI - Final BMI) / (Initial BMI-a)," where a is the reference point that defines the metric. The percentage of total weight loss (%TWL, a = 0) and percentage of excess weight loss (%EWL, a = 25) are influenced by a patient's initial weight. Recently, the percentage of alterable weight loss metric (%AWL, a = 13) has been reported to produce initial-weight-independent outcomes. OBJECTIVES: This study aimed to replicate the methodology used for %AWL determination in a Mediterranean cohort of bariatric patients. SETTINGS: Multicenter study in 10 large hospitals in Spain. METHODS: Two large prospective databases were retrospectively searched for all primary laparoscopic gastric bypass patients with 2 years of follow-up. Outcomes at nadir were expressed and analyzed with 26 different metrics (a from 0 to 25), looking for the metric whose outcomes produced (1) the lowest coefficient of variation, (2) no differences between initially lighter and heavier patients, and (3) no correlation with patients' initial BMI. RESULTS: A cohort of 1793 patients was stratified into 4 gender-age groups: younger women (YW, n = 733), older women (OW, n = 674), younger men (YM, n = 197), and older men (OM, n = 189). The calculations suggested an optimal reference point of 18 kg/m2, defining a new metric (percentage of Mediterranean alterable weight loss, %MAWL). When %TWL, %EWL, %AWL, and %MAWL were tested on the whole sample, only %MAWL produced initial-weight-independent results. CONCLUSIONS: In our Mediterranean cohort of patients, a reference point of 18 (and not 13) yielded initial-weight-independent outcomes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obesidad Mórbida / Derivación Gástrica / Laparoscopía Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Obes Surg Asunto de la revista: METABOLISMO Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obesidad Mórbida / Derivación Gástrica / Laparoscopía Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Obes Surg Asunto de la revista: METABOLISMO Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos