Differential gene expression in peritumoral brain zone of glioblastoma: role of SERPINA3 in promoting invasion, stemness and radioresistance of glioma cells and association with poor patient prognosis and recurrence.

Nimbalkar, Vidya P; Kruthika, Banavathy S; Sravya, Palavalasa; Rao, Shilpa; Sugur, Harsha S; Verma, Brijesh Kumar; Chickabasaviah, Yasha T; Arivazhagan, Arimappamagan; Kondaiah, Paturu; Santosh, Vani

Nimbalkar, Vidya P; Kruthika, Banavathy S; Sravya, Palavalasa; Rao, Shilpa; Sugur, Harsha S; Verma, Brijesh Kumar; Chickabasaviah, Yasha T; Arivazhagan, Arimappamagan; Kondaiah, Paturu; Santosh, Vani.

Afiliación

Nimbalkar VP; Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, 560029, India.
Kruthika BS; Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, 560029, India.
Sravya P; Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, 560029, India.
Rao S; Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, 560029, India.
Sugur HS; Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, 560029, India.
Verma BK; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, Karnataka, 560012, India.
Chickabasaviah YT; Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, 560029, India.
Arivazhagan A; Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, 560029, India.
Kondaiah P; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, Karnataka, 560012, India.
Santosh V; Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, 560029, India. vani.santosh@gmail.com.

J Neurooncol ; 152(1): 55-65, 2021 Mar.

Article en En | MEDLINE | ID: mdl-33389566

Asunto(s)

Biomarcadores de Tumor/metabolismo; Neoplasias Encefálicas/patología; Glioblastoma/patología; Serpinas/metabolismo; Adulto; Anciano; Biomarcadores de Tumor/genética; Neoplasias Encefálicas/genética; Neoplasias Encefálicas/metabolismo; Proliferación Celular/genética; Transición Epitelial-Mesenquimal/genética; Femenino; Glioblastoma/genética; Glioblastoma/metabolismo; Humanos; Masculino; Persona de Mediana Edad; Invasividad Neoplásica/genética; Recurrencia Local de Neoplasia/genética; Recurrencia Local de Neoplasia/metabolismo; Pronóstico; Tolerancia a Radiación/genética; Serpinas/genética; Transcriptoma; Adulto Joven

Palabras clave

Glioblastoma (GBM); Peritumoral brain zone (PBZ); Prognosis; Serine protease inhibitor clade A, member 3 (SERPINA3); Tumor recurrence

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Biomarcadores de Tumor / Serpinas / Glioblastoma Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Neurooncol Año: 2021 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos

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