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COVID-19 and congenital heart disease: a case series of nine children.
Haji Esmaeil Memar, Elmira; Pourakbari, Babak; Gorgi, Mojtaba; Sharifzadeh Ekbatani, Meisam; Navaeian, Amene; Khodabandeh, Mahmoud; Mahmoudi, Shima; Mamishi, Setareh.
Afiliación
  • Haji Esmaeil Memar E; Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Pourakbari B; Pediatric Infectious Disease Research Center, Tehran University of Medical Science, Tehran, Iran.
  • Gorgi M; Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Sharifzadeh Ekbatani M; Division of Pediatric Intensive Care Unit, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Navaeian A; Department of Infectious Diseases, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Khodabandeh M; Department of Infectious Diseases, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Mahmoudi S; Pediatric Infectious Disease Research Center, Tehran University of Medical Science, Tehran, Iran.
  • Mamishi S; Pediatric Infectious Disease Research Center, Tehran University of Medical Science, Tehran, Iran. smamishi@sina.tums.ac.ir.
World J Pediatr ; 17(1): 71-78, 2021 Feb.
Article en En | MEDLINE | ID: mdl-33387256
BACKGROUND: Coronavirus disease 2019 (COVID-19) is the current pandemic disease without any vaccine or efficient treatment to rescue the patients. Underlying diseases predispose the patients to a more severe disease and to a higher mortality rate. However, little evidence exists about COVID-19 outcomes in the pediatric population with congenital heart disease (CHD). Here, we report nine children with COVID-19 and concomitant CHD. METHODS: Our study included nine children with COVID-19 and concomitant CHD who were admitted to Children Medical Center Hospital during March and April 2020. The patients were classified based on the final outcome (death), and their clinical sign and symptoms, type of CHD, and drugs administered were compared. RESULTS: Among the nine patients, two died and we compared different characteristics, laboratory results and clinical findings of these cases based on the mortality. The deceased patients had severe types of CHD, worse arterial blood gases, severe clinical symptoms, higher mean level of partial thromboplastin time and C-reactive protein, and required more medications. CONCLUSIONS: The present study showed that the general consideration of mild COVID-19 in children does not include patients with CHD and that it is necessary to pay greater attention to children with CHD to determine guidelines for treatment of COVID-19 in these children. Owing to the scarcity of CHD and COVID-19, we reported only nine cases. However, further studies are highly required in this regard.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 / Cardiopatías Congénitas Tipo de estudio: Diagnostic_studies / Guideline Límite: Adolescent / Child, preschool / Female / Humans / Infant / Male / Newborn Idioma: En Revista: World J Pediatr Asunto de la revista: PEDIATRIA Año: 2021 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 / Cardiopatías Congénitas Tipo de estudio: Diagnostic_studies / Guideline Límite: Adolescent / Child, preschool / Female / Humans / Infant / Male / Newborn Idioma: En Revista: World J Pediatr Asunto de la revista: PEDIATRIA Año: 2021 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Suiza