Cross-subunit interactions that stabilize open states mediate gating in NMDA receptors.

Iacobucci, Gary J; Wen, Han; Helou, Matthew; Liu, Beiying; Zheng, Wenjun; Popescu, Gabriela K

Iacobucci, Gary J; Wen, Han; Helou, Matthew; Liu, Beiying; Zheng, Wenjun; Popescu, Gabriela K.

Afiliación

Iacobucci GJ; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, Buffalo, NY 14203.
Wen H; Department of Physics, College of Arts and Sciences, University at Buffalo, SUNY, Buffalo, NY 14260.
Helou M; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, Buffalo, NY 14203.
Liu B; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, Buffalo, NY 14203.
Zheng W; Department of Physics, College of Arts and Sciences, University at Buffalo, SUNY, Buffalo, NY 14260 wjzheng@buffalo.edu popescu@buffalo.edu.
Popescu GK; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, Buffalo, NY 14203; wjzheng@buffalo.edu popescu@buffalo.edu.

Proc Natl Acad Sci U S A ; 118(2)2021 01 12.

Article en En | MEDLINE | ID: mdl-33384330

Asunto(s)

Simulación de Dinámica Molecular; Receptores de N-Metil-D-Aspartato/metabolismo; Humanos; Cinética; Receptores de N-Metil-D-Aspartato/genética

Palabras clave

NMDA receptor; energy landscape; mutant cycle analysis; single molecule; targeted molecular dynamics

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de N-Metil-D-Aspartato / Simulación de Dinámica Molecular Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos

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