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Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation.
Rubiano, Andrés; Indapurkar, Amruta; Yokosawa, Ryosuke; Miedzik, Alina; Rosenzweig, Barry; Arefin, Ayesha; Moulin, Chloe M; Dame, Keri; Hartman, Neil; Volpe, Donna A; Matta, Murali K; Hughes, David J; Strauss, David G; Kostrzewski, Tomasz; Ribeiro, Alexandre J S.
Afiliación
  • Rubiano A; Center for Drug Evaluation and Research, Office of Translational Sciences, Office of Clinical Pharmacology, Division of Applied Regulatory Science, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Indapurkar A; Center for Drug Evaluation and Research, Office of Translational Sciences, Office of Clinical Pharmacology, Division of Applied Regulatory Science, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Yokosawa R; Center for Drug Evaluation and Research, Office of Translational Sciences, Office of Clinical Pharmacology, Division of Applied Regulatory Science, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Miedzik A; CN Bio Innovations Limited, Cambridge, UK.
  • Rosenzweig B; Center for Drug Evaluation and Research, Office of Translational Sciences, Office of Clinical Pharmacology, Division of Applied Regulatory Science, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Arefin A; Center for Drug Evaluation and Research, Office of Translational Sciences, Office of Clinical Pharmacology, Division of Applied Regulatory Science, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Moulin CM; Center for Drug Evaluation and Research, Office of Translational Sciences, Office of Clinical Pharmacology, Division of Applied Regulatory Science, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Dame K; Center for Drug Evaluation and Research, Office of Translational Sciences, Office of Clinical Pharmacology, Division of Applied Regulatory Science, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Hartman N; Center for Drug Evaluation and Research, Office of Translational Sciences, Office of Clinical Pharmacology, Division of Applied Regulatory Science, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Volpe DA; Center for Drug Evaluation and Research, Office of Translational Sciences, Office of Clinical Pharmacology, Division of Applied Regulatory Science, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Matta MK; Center for Drug Evaluation and Research, Office of Translational Sciences, Office of Clinical Pharmacology, Division of Applied Regulatory Science, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Hughes DJ; CN Bio Innovations Limited, Cambridge, UK.
  • Strauss DG; Center for Drug Evaluation and Research, Office of Translational Sciences, Office of Clinical Pharmacology, Division of Applied Regulatory Science, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Kostrzewski T; Center for Drug Evaluation and Research, Office of Translational Sciences, Office of Clinical Pharmacology, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Ribeiro AJS; CN Bio Innovations Limited, Cambridge, UK.
Clin Transl Sci ; 14(3): 1049-1061, 2021 05.
Article en En | MEDLINE | ID: mdl-33382907
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pruebas de Toxicidad / Cultivo Primario de Células / Hígado Tipo de estudio: Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: Clin Transl Sci Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pruebas de Toxicidad / Cultivo Primario de Células / Hígado Tipo de estudio: Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: Clin Transl Sci Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos