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Double-task exercise programmes to strengthen cognitive and vascular health in older adults at risk of cognitive decline: protocol for a randomised clinical trial.
Sánchez-Arenas, Rosalinda; Doubova, Svetlana V; Bernabe-Garcia, Mariela; Gregory, Michel A; Mejía-Alonso, Laura Alejandra; Orihuela-Rodríguez, Oscar; Paredes-Manjarrez, Carlos; Colín-Martínez, Tania; Mujica-Morales, Irene; Grijalva-Otero, Israel; Basurto-Acevedo, Lourdes; Manuel-Apolinar, Leticia; Cuadros-Moreno, Juan; Bernal-Diaz, Arcelia; Shigematsu, Ryosuke.
Afiliación
  • Sánchez-Arenas R; Epidemiology and Health Services Research Unit CMN Siglo XXI, Mexican Institute of Social Security, Mexico City, Mexico.
  • Doubova SV; Epidemiology and Health Services Research Unit CMN Siglo XXI, Mexican Institute of Social Security, Mexico City, Mexico svetlana.doubova@gmail.com.
  • Bernabe-Garcia M; Medical Research Unit in Nutrition, Pediatrics Hospital, National Medical Center Century XXI, Mexican Institute of Social Security, Mexico City, Mexico.
  • Gregory MA; School of Rehabilitation Sciences, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Mejía-Alonso LA; Rehabilitation Service, Specialty Hospital, National Medical Center Century XXI, Mexican Institute of Social Security, Mexico City, Mexico.
  • Orihuela-Rodríguez O; Cardiology Service, Specialty Hospital, National Medical Center Century XXI, Mexican Institute of Social Security, Mexico City, Mexico.
  • Paredes-Manjarrez C; Image Service, Specialty Hospital, National Medical Center Century XXI, Mexican Institute of Social Security, Mexico City, Mexico.
  • Colín-Martínez T; Continuous Admission Service, Specialty Hospital, National Medical Center Century XXI, Mexican Institute of Social Security, Mexico City, Mexico.
  • Mujica-Morales I; Division of Occupational Risk Prevention. Occupational Health Coordination, Mexican Institute of Social Security, Mexico City, Mexico.
  • Grijalva-Otero I; Medical Research Unit in Neurological Diseases, National Medical Center Century XXI, Mexican Institute of Social Security, Mexico City, Mexico.
  • Basurto-Acevedo L; Research Unit in Endocrine Diseases, National Medical Center Century XXI, Mexican Institute of Social Security, Mexico City, Mexico.
  • Manuel-Apolinar L; Research Unit in Endocrine Diseases, National Medical Center Century XXI, Mexican Institute of Social Security, Mexico City, Mexico.
  • Cuadros-Moreno J; Coordination of Health Education, Mexican Institute of Social Security, Mexico City, Mexico.
  • Bernal-Diaz A; Aragón School of Higher Education, National Autonomous University of Mexico, Mexico City, Mexico.
  • Shigematsu R; Faculty of Education, Mie University, Tsu, Mie, Japan.
BMJ Open ; 10(12): e039723, 2020 12 30.
Article en En | MEDLINE | ID: mdl-33380479
INTRODUCTION: Cognitive and physical declines are frequent causes of disability among older adults (OAs) in Mexico that imposes significant burden on the health system and OAs' families. Programmes to prevent or delay OAs' cognitive and physical decline are scarce. METHODS AND ANALYSIS: A double-blind randomised clinical trial will be conducted. The study will aim to evaluate two 24-week double-task (aerobic and cognitive) square-stepping exercise programmes for OAs at risk of cognitive decline-one programme with and another without caregiver participation-and to compare these with an aerobic-balance-stretching exercise programme (control group). 300 OAs (100 per group) affiliated with the Mexican Institute of Social Security (IMSS) between 60 and 65 years of age with self-reported cognitive concerns will participate. They will be stratified by education level and randomly allocated to the groups. The intervention will last 24 weeks, and the effect of each programme will be evaluated 12, 24 and 52 weeks after the intervention. Participants' demographic and clinical characteristics will be collected at baseline. The outcomes will include: (1) general cognitive function; (2) specific cognitive functions; (3) dual-task gait; (4) blood pressure; (5) carotid intima-media thickness; (6) OAs' health-related quality of life; and (7) caregiver burden. The effects of the interventions on each outcome variable will be examined using a repeated-measures analysis of variance (ANOVA), with study groups as the between-subjects variable and time as the within-subject variable. ETHICS AND DISSEMINATION: The study was approved by the IMSS Ethics and Research Committees (registration number: 2018-785-095). All participants will sign a consent form prior to their participation. The study results will be disseminated to the IMSS authorities, healthcare providers and the research community. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov (NCT04068376).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Disfunción Cognitiva Tipo de estudio: Clinical_trials / Etiology_studies / Guideline / Risk_factors_studies Aspecto: Ethics / Patient_preference Límite: Aged / Humans País/Región como asunto: Mexico Idioma: En Revista: BMJ Open Año: 2020 Tipo del documento: Article País de afiliación: México Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Disfunción Cognitiva Tipo de estudio: Clinical_trials / Etiology_studies / Guideline / Risk_factors_studies Aspecto: Ethics / Patient_preference Límite: Aged / Humans País/Región como asunto: Mexico Idioma: En Revista: BMJ Open Año: 2020 Tipo del documento: Article País de afiliación: México Pais de publicación: Reino Unido