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Hazardous Alcohol Use, Impulsivity, and HIV-Risk Behavior Among HIV-Positive Russian Patients With a History of Injection Drug Use.
Chavez, Kathryn; Palfai, Tibor P; Cheng, Debbie M; Blokhina, Elena; Gnatienko, Natalia; Quinn, Emily K; Krupitsky, Evgeny; Samet, Jeffrey H.
Afiliación
  • Chavez K; Department of Psychological and Brain Sciences, Boston University, Boston, Massachusetts.
  • Palfai TP; Department of Psychological and Brain Sciences, Boston University, Boston, Massachusetts.
  • Cheng DM; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
  • Blokhina E; First St. Petersburg Pavlov State Medical University, St. Petersburg, Russian Federation.
  • Gnatienko N; Clinical Addiction Research and Education (CARE) Unit, Department of Medicine, Section of General Internal Medicine, Boston University School of Medicine/Boston Medical Center, Boston, Massachusetts.
  • Quinn EK; Biostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, Massachusetts, USA.
  • Krupitsky E; First St. Petersburg Pavlov State Medical University, St. Petersburg, Russian Federation.
  • Samet JH; Department of Addictions, Bekhterev Psychoneurological Research Institute, St. Petersburg, Russian Federation.
Am J Addict ; 30(2): 164-172, 2021 03.
Article en En | MEDLINE | ID: mdl-33378082
BACKGROUND AND OBJECTIVES: Previous findings on the association between hazardous drinking and HIV-risk behavior have been equivocal, varying by population and individual difference factors. This study examined associations between hazardous drinking, impulsivity, and HIV-risk behaviors among HIV-positive Russian patients with a history of injection drug use (IDU), not on antiretroviral therapy. METHODS: Negative binomial regression analyses of data from a randomized controlled trial were performed (N = 241). Main independent variables were the Alcohol Use Disorders Identification Test and the Barratt Impulsiveness Scale. Outcomes were number of condomless sexual episodes (CSE; primary), number of sexual partners, and needle-sharing frequency (secondary). RESULTS: Hazardous drinking was positively associated with the frequency of CSE (adjusted incidence rate ratio [aIRR] = 2.16, 95% confidence interval [CI], 1.98-2.36). Moderate (aIRR = 0.51, 95% CI, 0.46-0.56) and high (aIRR = 0.66, 95% CI, 0.60-0.73) impulsivity were associated with fewer CSE compared with low impulsivity. Hazardous drinking (aIRR = 0.64, 95% CI, 0.52-0.79) and impulsivity (aIRR = 0.95, 95% CI, 0.94-0.96) were both associated with fewer sexual partners. Hazardous drinking and impulsivity were each associated with increased needle sharing. The association between hazardous drinking and number of needle-shares was strongest at higher impulsivity levels. CONCLUSION AND SCIENTIFIC SIGNIFICANCE: Hazardous drinking may be a risk factor for CSE among HIV-positive Russian patients and may influence needle sharing. Findings contribute to our understanding of the interactive associations between hazardous drinking and impulsivity with sexual risk behaviors and needle sharing among HIV-positive Russian patients with a history of IDU. (Am J Addict 2020;00:00-00).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asunción de Riesgos / Infecciones por VIH / Alcoholismo / Conducta Impulsiva Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Asia / Europa Idioma: En Revista: Am J Addict Asunto de la revista: TRANSTORNOS RELACIONADOS COM SUBSTANCIAS Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asunción de Riesgos / Infecciones por VIH / Alcoholismo / Conducta Impulsiva Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Asia / Europa Idioma: En Revista: Am J Addict Asunto de la revista: TRANSTORNOS RELACIONADOS COM SUBSTANCIAS Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido