Treatment of non-toxic multinodular goiter with radioactive iodine.
Am J Med
; 84(1): 19-22, 1988 Jan.
Article
en En
| MEDLINE
| ID: mdl-3337130
Fourteen patients with large non-toxic multinodular goiters were treated with 20 to 100 mCi (740 to 3,700 MBq) of radioactive iodine (iodine-131). In seven, the goiter had recurred after a partial thyroidectomy and four of these had had two operations. Eight had symptoms of respiratory obstruction, two had dysphagia, and the others sought treatment for cosmetic reasons. After administration of iodine-131, there was a significant decrease in goiter size in 11 of the 14 patients, and all those with obstructive symptoms showed improvement. No significant local side effects occurred, but hypothyroidism and Graves' disease each occurred once during follow-up from one to 13 years. Radioactive iodine in doses of 20 to 100 mCi is an effective, safe therapeutic alternative in patients with large non-toxic multinodular goiter, particularly when there is recurrence following surgery or when there are contraindications to surgery.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bocio Nodular
/
Radioisótopos de Yodo
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Am J Med
Año:
1988
Tipo del documento:
Article
País de afiliación:
Australia
Pais de publicación:
Estados Unidos