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Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration.
Hargrove-Grimes, Passley; Mondal, Anupam K; Gumerson, Jessica; Nellissery, Jacob; Aponte, Angel M; Gieser, Linn; Qian, Haohua; Fariss, Robert N; Bonifacino, Juan S; Li, Tiansen; Swaroop, Anand.
Afiliación
  • Hargrove-Grimes P; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Mondal AK; Institute of Biomedical Sciences, George Washington University, Washington, District of Columbia, United States of America.
  • Gumerson J; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Nellissery J; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Aponte AM; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Gieser L; Proteomics Core, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Qian H; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Fariss RN; Visual Function Core, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Bonifacino JS; Biological Imaging Core, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Li T; Neurosciences and Cellular and Structural Biology Division, Eunice Kennedy Shriver National Institute for Child Health and Development, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Swaroop A; Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
PLoS Genet ; 16(12): e1009259, 2020 12.
Article en En | MEDLINE | ID: mdl-33362196
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Fotorreceptoras / Degeneración Retiniana / Autofagia / Factores de Intercambio de Guanina Nucleótido / Endocitosis / Neurogénesis Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Fotorreceptoras / Degeneración Retiniana / Autofagia / Factores de Intercambio de Guanina Nucleótido / Endocitosis / Neurogénesis Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos