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The chromatin landscape of primary synovial sarcoma organoids is linked to specific epigenetic mechanisms and dependencies.
Boulay, Gaylor; Cironi, Luisa; Garcia, Sara P; Rengarajan, Shruthi; Xing, Yu-Hang; Lee, Lukuo; Awad, Mary E; Naigles, Beverly; Iyer, Sowmya; Broye, Liliane C; Keskin, Tugba; Cauderay, Alexandra; Fusco, Carlo; Letovanec, Igor; Chebib, Ivan; Nielsen, Petur Gunnalugur; Tercier, Stéphane; Cherix, Stéphane; Nguyen-Ngoc, Tu; Cote, Gregory; Choy, Edwin; Provero, Paolo; Suvà, Mario L; Rivera, Miguel N; Stamenkovic, Ivan; Riggi, Nicolò.
Afiliación
  • Boulay G; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Cironi L; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Garcia SP; Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Rengarajan S; Swiss Cancer Center Leman, Centre Hospitalier Universitaire Vaudois, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Xing YH; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Lee L; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Awad ME; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Naigles B; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Iyer S; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Broye LC; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Keskin T; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Cauderay A; Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Fusco C; Swiss Cancer Center Leman, Centre Hospitalier Universitaire Vaudois, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Letovanec I; Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Chebib I; Swiss Cancer Center Leman, Centre Hospitalier Universitaire Vaudois, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Nielsen PG; Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Tercier S; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Cherix S; Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Nguyen-Ngoc T; Swiss Cancer Center Leman, Centre Hospitalier Universitaire Vaudois, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Cote G; Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Choy E; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Provero P; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Suvà ML; Department of Woman-Mother Child, Centre Hospitalier Universitaire Vaudois, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Rivera MN; Department of Orthopedics, Faculty of Biology and Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
  • Stamenkovic I; Department of Oncology, Centre Hospitalier Universitaire Vaudois, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Riggi N; Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Life Sci Alliance ; 4(2)2021 02.
Article en En | MEDLINE | ID: mdl-33361335
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromatina / Regulación Neoplásica de la Expresión Génica / Sarcoma Sinovial / Ensamble y Desensamble de Cromatina / Epigénesis Genética Límite: Humans Idioma: En Revista: Life Sci Alliance Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromatina / Regulación Neoplásica de la Expresión Génica / Sarcoma Sinovial / Ensamble y Desensamble de Cromatina / Epigénesis Genética Límite: Humans Idioma: En Revista: Life Sci Alliance Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos