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Cardiopulmonary resuscitation in quaternary neonatal intensive care units: a multicenter study.
Ali, Noorjahan; Lam, Teresa; Gray, Megan M; Clausen, David; Riley, Melissa; Grover, Theresa R; Sawyer, Taylor.
Afiliación
  • Ali N; Department of Pediatrics, Division of Perinatal-Neonatal Medicine, UT Southwestern of Dallas, Children's Medical Center of Dallas, TX, United States. Electronic address: noorjahan.ali@utsouthwestern.edu.
  • Lam T; Department of Pediatrics, Division of Perinatal-Neonatal Medicine, University of Washington, School of Medicine, Seattle, Washington, United States.
  • Gray MM; Department of Pediatrics, Division of Perinatal-Neonatal Medicine, University of Washington, School of Medicine, Seattle, Washington, United States.
  • Clausen D; Department of Biostatistics, University of Washington, United States.
  • Riley M; Department of Pediatrics, Division of Perinatal-Neonatal Medicine, UPMC Children's Hospital of Pittsburgh, Pennsylvania, United States.
  • Grover TR; University of Colorado School of Medicine, Section of Neonatology and Children's Hospital Colorado, United States.
  • Sawyer T; Department of Pediatrics, Division of Perinatal-Neonatal Medicine, University of Washington, School of Medicine, Seattle, Washington, United States.
Resuscitation ; 159: 77-84, 2021 02.
Article en En | MEDLINE | ID: mdl-33359416
BACKGROUND: The reported incidence of cardiopulmonary resuscitation (CPR) in quaternary NICU is approximately 10-times higher than in the delivery room. However, the etiologies and outcomes of CPR in quaternary NICUs are poorly understood. We hypothesized that demographic characteristics, diagnoses, interventions, and arrest etiologies would be associated with survival to discharge after CPR. METHODS: Multicenter retrospective cohort study of four quaternary NICUs over six years (2011-2016). Demographics, resuscitation event data, and post-arrest outcomes were analyzed. The primary outcome was survival to discharge. RESULTS: Of 17,358 patients admitted to four NICUs, 200 (1.1%) experienced a CPR event, and 45.5% of those survived to discharge. Acute respiratory compromise leading to cardiopulmonary arrest occurred in 182 (91%) of the CPR events. Most neonates requiring CPR were on mechanical ventilation (79%) and had central venous access (90%) at the time of arrest. Treatments at the time of the arrest associated with decreased survival to discharge included mechanical ventilation, antibiotics, or vasopressor therapy (p < 0.01). Etiologies of arrest associated with decreased survival to discharge included multisystem organ failure, septic shock, and pneumothorax (p < 0.05). Longer duration of CPR was associated with decreased survival to discharge. The odds of surviving to discharge decreased for infants who had a primarily cardiac arrest and for infants who received epinephrine during the arrest. CONCLUSION: Approximately 1% of neonates admitted to quaternary NICUs require CPR. The most common etiology of arrest is acute respiratory compromise on a ventilator. CPR events with respiratory etiology have a favorable outcome as compared to non-respiratory causes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reanimación Cardiopulmonar / Paro Cardíaco Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans / Infant / Newborn Idioma: En Revista: Resuscitation Año: 2021 Tipo del documento: Article Pais de publicación: Irlanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reanimación Cardiopulmonar / Paro Cardíaco Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans / Infant / Newborn Idioma: En Revista: Resuscitation Año: 2021 Tipo del documento: Article Pais de publicación: Irlanda