Virtual screening of the multi-gene regulatory molecular mechanism of Si-Wu-tang against non-triple-negative breast cancer based on network pharmacology combined with experimental validation.

Zhang, Zeye; Liu, Jia; Liu, Yifan; Shi, Danning; He, Yueshuang; Zhao, Piwen

Zhang, Zeye; Liu, Jia; Liu, Yifan; Shi, Danning; He, Yueshuang; Zhao, Piwen.

Afiliación

Zhang Z; School of Life Sciences, Beijing University of Chinese Medicine, No.11 East Road, North 3rd Ring Road, Beijing, 100029, China. Electronic address: 20180931185@bucm.edu.cn.
Liu J; School of Life Sciences, Beijing University of Chinese Medicine, No.11 East Road, North 3rd Ring Road, Beijing, 100029, China. Electronic address: 20190941089@bucm.edu.cn.
Liu Y; Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, 100700, China. Electronic address: 304210893@qq.com.
Shi D; School of Life Sciences, Beijing University of Chinese Medicine, No.11 East Road, North 3rd Ring Road, Beijing, 100029, China. Electronic address: shidanning@bucm.edu.cn.
He Y; School of Life Sciences, Beijing University of Chinese Medicine, No.11 East Road, North 3rd Ring Road, Beijing, 100029, China. Electronic address: heyueshuang@163.com.
Zhao P; School of Life Sciences, Beijing University of Chinese Medicine, No.11 East Road, North 3rd Ring Road, Beijing, 100029, China. Electronic address: pw__zhao@163.com.

J Ethnopharmacol ; 269: 113696, 2021 Apr 06.

Article en En | MEDLINE | ID: mdl-33358854

Asunto(s)

Antineoplásicos Fitogénicos/química; Antineoplásicos Fitogénicos/farmacología; Neoplasias de la Mama/tratamiento farmacológico; Medicamentos Herbarios Chinos/química; Medicamentos Herbarios Chinos/farmacología; Apoptosis/efectos de los fármacos; Catalasa/biosíntesis; Catalasa/genética; Ciclooxigenasa 2/genética; Bases de Datos de Compuestos Químicos; Bases de Datos Genéticas; Metabolismo Energético/efectos de los fármacos; Receptor alfa de Estrógeno/biosíntesis; Receptor alfa de Estrógeno/genética; Femenino; Regulación Neoplásica de la Expresión Génica; Redes Reguladoras de Genes; Humanos; Estimación de Kaplan-Meier; Células MCF-7; Medicina Tradicional China/métodos; Simulación del Acoplamiento Molecular; PPAR gamma/biosíntesis; PPAR gamma/genética; Unión Proteica; Mapas de Interacción de Proteínas

Palabras clave

Molecular docking; Network pharmacology; Non-TNBC; Si-Wu-tang (SWT)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Medicamentos Herbarios Chinos / Antineoplásicos Fitogénicos Tipo de estudio: Diagnostic_studies / Screening_studies / Systematic_reviews Límite: Female / Humans Idioma: En Revista: J Ethnopharmacol Año: 2021 Tipo del documento: Article Pais de publicación: Irlanda

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