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Biotechnological Applications of Proteases in Food Technology.
Tavano, Olga Luisa; Berenguer-Murcia, Angel; Secundo, Francesco; Fernandez-Lafuente, Roberto.
Afiliación
  • Tavano OL; Faculty of Nutrition, Alfenas Federal Univ., 700 Gabriel Monteiro da Silva St, Alfenas, MG 37130-000, Brazil.
  • Berenguer-Murcia A; Inorganic Chemistry Dept. and Materials Science Inst., Alicante Univ., Ap. 99, E-03080, Alicante, Spain.
  • Secundo F; Istit. di Chimica del Riconoscimento Molecolare, CNR, v. Mario Bianco 9, 20131 Milan, Italy.
  • Fernandez-Lafuente R; Dept. of Biocatalysis, ICP - CSIC. Campus UAM-CSIC. Cantoblanco, ZC 28049, Madrid, Spain.
Compr Rev Food Sci Food Saf ; 17(2): 412-436, 2018 Mar.
Article en En | MEDLINE | ID: mdl-33350076
This review presents some of the hottest topics in biotechnological applications: proteases in biocatalysis. Obviously, one of the most relevant areas of application is in the hydrolysis of proteins in food technology, and that has led to a massive use on proteomics. The aim is to identify via peptide maps the different proteins obtained after a specific protease hydrolysis. However, concepts like degradomics are also taking on a more relevant importance in the use and study of proteases and will also be discussed. Other protease applications, as seem in cleaning (detergent development), the pharmaceutical industry, and in fine chemistry, will be analyzed. This review progresses from basic areas such as protease classification to a discussion of the preparation of protease-immobilized biocatalysts, considering the different problems raised by the use of immobilized proteases due to the peculiar features of the substrates, usually large macromolecules. Production of bioactive peptides via limited hydrolysis of proteins will occupy an important place in this review.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Compr Rev Food Sci Food Saf Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Compr Rev Food Sci Food Saf Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos