Synthesis of carbazole based &#945;-aminophosphonate derivatives: design, molecular docking and <i>in vitro</i> cholinesterase activity.

Shaikh, Sarfaraz; Dhavan, Pratik; Singh, Pinky; Uparkar, Jasmin; Vaidya, S P; Jadhav, B L; Ramana, M V

Synthesis of carbazole based α-aminophosphonate derivatives: design, molecular docking and in vitro cholinesterase activity.

Shaikh, Sarfaraz; Dhavan, Pratik; Singh, Pinky; Uparkar, Jasmin; Vaidya, S P; Jadhav, B L; Ramana, M V.

Afiliación

Shaikh S; Department of Chemistry, University of Mumbai, Mumbai, India.
Dhavan P; Department of Life sciences, University of Mumbai, Mumbai, India.
Singh P; Biology Department, Haffkine Institute, Parel, Mumbai, India.
Uparkar J; Department of Chemistry, University of Mumbai, Mumbai, India.
Vaidya SP; Biology Department, Haffkine Institute, Parel, Mumbai, India.
Jadhav BL; Department of Life sciences, University of Mumbai, Mumbai, India.
Ramana MV; Department of Chemistry, University of Mumbai, Mumbai, India.

J Biomol Struct Dyn ; 40(11): 4801-4814, 2022 07.

Article en En | MEDLINE | ID: mdl-33345710

Asunto(s)

Acetilcolinesterasa; Inhibidores de la Colinesterasa; Acetilcolinesterasa/química; Carbazoles/farmacología; Inhibidores de la Colinesterasa/química; Peróxido de Hidrógeno; Simulación del Acoplamiento Molecular; Estructura Molecular; Relación Estructura-Actividad

Palabras clave

Cholinesterase inhibitors; DPPH scavenging; cell viability; enzyme kinetics; molecular docking

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetilcolinesterasa / Inhibidores de la Colinesterasa Idioma: En Revista: J Biomol Struct Dyn Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Reino Unido

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