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Early Complications With Preloaded Descemet Membrane Endothelial Keratoplasty Are Not Dependent on Optisol-GS Washout or Trypan Blue Restaining.
Greenwald, Miles F; Nanji, Afshan A; Clements, John L; Stutzman, Richard D; Stoeger, Christopher G; Chamberlain, Winston D.
Afiliación
  • Greenwald MF; Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR.
  • Nanji AA; Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR.
  • Clements JL; Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR.
  • Stutzman RD; Department of Ophthalmology, Veterans Affairs Medical Center, Portland, OR; and.
  • Stoeger CG; Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR.
  • Chamberlain WD; Lions Vision Gift, Portland, OR.
Cornea ; 40(11): 1402-1405, 2021 Nov 01.
Article en En | MEDLINE | ID: mdl-33332894
PURPOSE: To describe the intraoperative and early postoperative complications using preloaded Descemet membrane endothelial keratoplasty (DMEK) grafts with intraocular injection of the graft in Optisol-GS and omission of trypan blue restaining. METHODS: This is a retrospective case series of 132 consecutive eyes with Fuchs endothelial dystrophy or endothelial failure who underwent DMEK using preloaded donor tissue prepared as previously described. The graft was not restained with trypan blue by the surgeon, and Optisol-GS was injected with the graft into the eye instead of being rinsed from the injector. Early postoperative complications (0-8 wk) including intraoperative fibrin formation, intraocular inflammation, elevated intraocular pressure, partial graft detachment requiring rebubble, and early graft failure were recorded. RESULTS: No eyes developed intraoperative fibrin formation or postoperative inflammation (such as toxic anterior segment syndrome) or elevated intraocular pressure. For eyes with Fuchs corneal dystrophy, our rebubble rate was 21% (22/106 eyes). Early graft failure was noted in 2% (3/132 eyes), which is similar to previous reports. CONCLUSIONS: Our results suggest that injection of Optisol-GS into the anterior chamber during DMEK graft injection does not lead to increases in intraoperative or early postoperative complications. Trypan blue restaining is not necessary for intraoperative visualization. This simplification can reduce graft manipulation and save time and resources for this procedure.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Donantes de Tejidos / Azul de Tripano / Endotelio Corneal / Gentamicinas / Sulfatos de Condroitina / Dextranos / Pérdida de Celulas Endoteliales de la Córnea / Queratoplastia Endotelial de la Lámina Limitante Posterior Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male Idioma: En Revista: Cornea Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Donantes de Tejidos / Azul de Tripano / Endotelio Corneal / Gentamicinas / Sulfatos de Condroitina / Dextranos / Pérdida de Celulas Endoteliales de la Córnea / Queratoplastia Endotelial de la Lámina Limitante Posterior Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male Idioma: En Revista: Cornea Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos