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Analgesic effect of ropivacaine with fentanyl in comparison with ropivacaine alone for continuous femoral nerve block after knee replacement arthroplasty: a prospective, randomized, double-blinded study.
Kim, Gunn Hee; Lee, Joon Woo; Kim, Go Eun; Lee, Seong Su; Son, Shill Lee; Kim, Byung Uk; Cho, Ha Na; Kwon, Mi Young; Koo, Min Seok; Kim, Ji Eun; Yun, Mi Jung.
Afiliación
  • Kim GH; Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea.
  • Lee JW; Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea.
  • Kim GE; Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea.
  • Lee SS; Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea.
  • Son SL; Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea.
  • Kim BU; Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea.
  • Cho HN; Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea.
  • Kwon MY; Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea.
  • Koo MS; Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea.
  • Kim JE; Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea.
  • Yun MJ; Department of Anesthesiology and Pain Medicine, National Medical Center, Seoul, Korea.
Anesth Pain Med (Seoul) ; 15(2): 209-216, 2020 Apr 30.
Article en En | MEDLINE | ID: mdl-33329816
BACKGROUND: The analgesic effect of perineural opioid in clinical practice are still controversial. This randomized controlled trial compared analgesic effect of ropivacaine with fentanyl or ropivacaine alone for continuous femoral nerve block following unilateral total knee arthroplasty. METHODS: Fourty patients of ASA PS Ⅰ or Ⅱ receiving total knee arthroplasty with spinal anesthesia were enlisted and randomly allocated into two groups. Group R; bolus injection of 0.375% ropivacaine, 30 ml and an infusion of 0.2% ropivacaine at 8 ml/h (n = 20). Group RF; 0.375% ropivacaine, 29 ml added with 50 µg of fentanyl as a bolus and an infusion of 0.2% ropivacaine mixed with 1 µg/ml of fentanyl at 8 ml/h (n = 20). Local anesthetic infusion via a femoral nerve catheter was started at the end of operation and continued for 48 h. Intravenous patient-controlled analgesia with hydromorphone (0.15 mg/ml, 0-1-10) were used for adjuvant analgesics. Position of catheter tip and contrast distribution, visual analogue scale of pain, hydromorphone consumption, side effects were recorded for 48 h after operation. Patient satisfaction for the pain control received were noted. RESULTS: The pain visual analogue scale, incidences of side effects and satisfaction were not different between the two groups (P > 0.05), but the hydromorphone usage at 48 h after operation were lower in the Group RF than in the Group R (P = 0.047). CONCLUSIONS: The analgesic effect of ropivacaine with fentanyl for continuous femoral nerve block after knee replacement arthroplasty was not superior to that of the ropivacaine alone.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Risk_factors_studies Idioma: En Revista: Anesth Pain Med (Seoul) Año: 2020 Tipo del documento: Article Pais de publicación: Corea del Sur

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Risk_factors_studies Idioma: En Revista: Anesth Pain Med (Seoul) Año: 2020 Tipo del documento: Article Pais de publicación: Corea del Sur