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Hypomorph mutation-directed small-molecule protein-protein interaction inducers to restore mutant SMAD4-suppressed TGF-ß signaling.
Tang, Cong; Mo, Xiulei; Niu, Qiankun; Wahafu, Alafate; Yang, Xuan; Qui, Min; Ivanov, Andrey A; Du, Yuhong; Fu, Haian.
Afiliación
  • Tang C; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA 30322, USA; The First Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an, Shannxi 710061, P.R.China.
  • Mo X; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address: xmo@emory.edu.
  • Niu Q; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Wahafu A; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA 30322, USA; The First Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an, Shannxi 710061, P.R.China.
  • Yang X; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA 30322, USA; Emory Chemical Biology Discovery Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Qui M; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA 30322, USA; Emory Chemical Biology Discovery Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Ivanov AA; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA 30322, USA; Emory Chemical Biology Discovery Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Du Y; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA 30322, USA; Emory Chemical Biology Discovery Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Fu H; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA 30322, USA; Emory Chemical Biology Discovery Center, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Hematology and Medical Oncology and Winship Cancer Institute, Emory Univer
Cell Chem Biol ; 28(5): 636-647.e5, 2021 05 20.
Article en En | MEDLINE | ID: mdl-33326750
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor de Crecimiento Transformador beta / Proteína Smad4 / Bibliotecas de Moléculas Pequeñas / Indoles Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: Cell Chem Biol Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor de Crecimiento Transformador beta / Proteína Smad4 / Bibliotecas de Moléculas Pequeñas / Indoles Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: Cell Chem Biol Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos