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Skin-interfaced microfluidic system with personalized sweating rate and sweat chloride analytics for sports science applications.
Baker, Lindsay B; Model, Jeffrey B; Barnes, Kelly A; Anderson, Melissa L; Lee, Stephen P; Lee, Khalil A; Brown, Shyretha D; Reimel, Adam J; Roberts, Timothy J; Nuccio, Ryan P; Bonsignore, Justina L; Ungaro, Corey T; Carter, James M; Li, Weihua; Seib, Melissa S; Reeder, Jonathan T; Aranyosi, Alexander J; Rogers, John A; Ghaffari, Roozbeh.
Afiliación
  • Baker LB; Gatorade Sports Science Institute, PepsiCo R&D Life Sciences, Barrington, IL 60010, USA. lindsay.baker@pepsico.com jrogers@northwestern.edu rooz@northwestern.edu.
  • Model JB; Epicore Biosystems Inc, Cambridge, MA 02139, USA.
  • Barnes KA; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.
  • Anderson ML; Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA.
  • Lee SP; Gatorade Sports Science Institute, PepsiCo R&D Life Sciences, Barrington, IL 60010, USA.
  • Lee KA; Gatorade Sports Science Institute, PepsiCo R&D Life Sciences, Bradenton, FL 34210, USA.
  • Brown SD; Epicore Biosystems Inc, Cambridge, MA 02139, USA.
  • Reimel AJ; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.
  • Roberts TJ; Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA.
  • Nuccio RP; Gatorade Sports Science Institute, PepsiCo R&D Life Sciences, Bradenton, FL 34210, USA.
  • Bonsignore JL; Gatorade Sports Science Institute, PepsiCo R&D Life Sciences, Barrington, IL 60010, USA.
  • Ungaro CT; Gatorade Sports Science Institute, PepsiCo R&D Life Sciences, Barrington, IL 60010, USA.
  • Carter JM; Gatorade Sports Science Institute, PepsiCo R&D Life Sciences, Bradenton, FL 34210, USA.
  • Li W; Gatorade Sports Science Institute, PepsiCo R&D Life Sciences, Barrington, IL 60010, USA.
  • Seib MS; Gatorade Sports Science Institute, PepsiCo R&D Life Sciences, Bradenton, FL 34210, USA.
  • Reeder JT; Gatorade Sports Science Institute, PepsiCo R&D Life Sciences, Barrington, IL 60010, USA.
  • Aranyosi AJ; Gatorade Sports Science Institute, PepsiCo R&D Life Sciences, Leicester, UK.
  • Rogers JA; Epicore Biosystems Inc, Cambridge, MA 02139, USA.
  • Ghaffari R; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.
Sci Adv ; 6(50)2020 12.
Article en En | MEDLINE | ID: mdl-33310859
Advanced capabilities in noninvasive, in situ monitoring of sweating rate and sweat electrolyte losses could enable real-time personalized fluid-electrolyte intake recommendations. Established sweat analysis techniques using absorbent patches require post-collection harvesting and benchtop analysis of sweat and are thus impractical for ambulatory use. Here, we introduce a skin-interfaced wearable microfluidic device and smartphone image processing platform that enable analysis of regional sweating rate and sweat chloride concentration ([Cl-]). Systematic studies (n = 312 athletes) establish significant correlations for regional sweating rate and sweat [Cl-] in a controlled environment and during competitive sports under varying environmental conditions. The regional sweating rate and sweat [Cl-] results serve as inputs to algorithms implemented on a smartphone software application that predicts whole-body sweating rate and sweat [Cl-]. This low-cost wearable sensing approach could improve the accessibility of physiological insights available to sports scientists, practitioners, and athletes to inform hydration strategies in real-world ambulatory settings.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Sci Adv Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Sci Adv Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos