Micro-RNA Analysis in Pulmonary Arterial Hypertension: Current Knowledge and Challenges.

Santos-Ferreira, Cátia A; Abreu, Mónica T; Marques, Carla I; Gonçalves, Lino M; Baptista, Rui; Girão, Henrique M

Santos-Ferreira, Cátia A; Abreu, Mónica T; Marques, Carla I; Gonçalves, Lino M; Baptista, Rui; Girão, Henrique M.

Afiliación

Santos-Ferreira CA; Cardiology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Abreu MT; Clinical Academic Centre of Coimbra, Coimbra, Portugal.
Marques CI; University of Coimbra, Coimbra Institute for Clinical and Biomedical Research, Faculty of Medicine, Coimbra, Portugal.
Gonçalves LM; University of Coimbra, Center for Innovative Biomedicine and Biotechnology, Coimbra, Portugal.
Baptista R; Clinical Academic Centre of Coimbra, Coimbra, Portugal.
Girão HM; University of Coimbra, Coimbra Institute for Clinical and Biomedical Research, Faculty of Medicine, Coimbra, Portugal.

JACC Basic Transl Sci ; 5(11): 1149-1162, 2020 Nov.

Article en En | MEDLINE | ID: mdl-33294743

Palabras clave

BMPR2, bone morphogenetic protein receptor type 2; EPC, endothelial progenitor cell; HIF, hypoxia-inducible factor; HPAH, hereditary pulmonary arterial hypertension; MCT, monocrotaline; PAAF, pulmonary arterial adventitial fibroblast; PAEC, pulmonary artery endothelial cell; PAH, pulmonary arterial hypertension; PASMC, pulmonary artery smooth muscle cells; PH, pulmonary hypertension; RV, right ventricle; SU/Hx/Nx, association of Sugen 5416 with chronic hypoxia followed by normoxia; WHO, World Health Organization; animal model; lncRNA, long noncoding RNA; mRNA, messenger RNA; miRNA, micro-RNA; micro-RNA; microarray; ncRNAs, noncoding RNAs; pulmonary arterial hypertension

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: JACC Basic Transl Sci Año: 2020 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: Estados Unidos

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