Activation of silent information regulator 1 exerts a neuroprotective effect after intracerebral hemorrhage by deacetylating NF-&#954;B/p65.

Deng, Hong-Ji; Zhou, Chen-Hui; Huang, Li-Tian; Wen, Liang-Bao; Zhou, Meng-Liang; Wang, Chun-Xi

Activation of silent information regulator 1 exerts a neuroprotective effect after intracerebral hemorrhage by deacetylating NF-κB/p65.

Deng, Hong-Ji; Zhou, Chen-Hui; Huang, Li-Tian; Wen, Liang-Bao; Zhou, Meng-Liang; Wang, Chun-Xi.

Afiliación

Deng HJ; Department of Neurosurgery, the First Affiliated Hospital, Guangxi Medical University, Nanning, China.
Zhou CH; Department of Neurosurgery, Ningbo First Hospital, Ningbo University School of Medicine, Ningbo, China.
Huang LT; Department of Neurosurgery, the First Affiliated Hospital, Guangxi Medical University, Nanning, China.
Wen LB; Department of Neurosurgery, the First Affiliated Hospital, Guangxi Medical University, Nanning, China.
Zhou ML; Department of Neurosurgery, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Wang CX; Department of Neurosurgery, the First Affiliated Hospital, Guangxi Medical University, Nanning, China.

J Neurochem ; 157(3): 574-585, 2021 05.

Article en En | MEDLINE | ID: mdl-33289070

Asunto(s)

Hemorragia Cerebral/tratamiento farmacológico; Fármacos Neuroprotectores; Sirtuina 1/genética; Factor de Transcripción ReIA/efectos de los fármacos; Acetilación; Animales; Apoptosis/efectos de los fármacos; Hemorragia Cerebral/inducido químicamente; Colagenasas; Encefalitis/tratamiento farmacológico; Encefalitis/patología; Hemoglobinas; Inyecciones Intraventriculares; Interleucina-1beta/efectos de los fármacos; Masculino; Ratones; Ratones Endogámicos C57BL; Neuronas/efectos de los fármacos; Cultivo Primario de Células; Resveratrol/uso terapéutico; Sirtuina 1/efectos de los fármacos; Factor de Transcripción ReIA/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

NF-κB; SIRT1; intracerebral hemorrhage; neuroinflammatory

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemorragia Cerebral / Fármacos Neuroprotectores / Factor de Transcripción ReIA / Sirtuina 1 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Neurochem Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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