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The G protein coupled receptor CXCR4 designed by the QTY code becomes more hydrophilic and retains cell signaling activity.
Tegler, Lotta; Corin, Karolina; Pick, Horst; Brookes, Jennifer; Skuhersky, Michael; Vogel, Horst; Zhang, Shuguang.
Afiliación
  • Tegler L; Center for Bits and Atoms, Massachusetts Institute of Technology, Cambridge, MA, 02139-4307, USA.
  • Corin K; Molecular Biotechnology/IFM, Linköping University, 58183, Linköping, Sweden.
  • Pick H; Center for Bits and Atoms, Massachusetts Institute of Technology, Cambridge, MA, 02139-4307, USA. kcorin@gmail.com.
  • Brookes J; Biomedical Engineering Research Group, School of Electrical and Information Engineering, and Department of Molecular Medicine and Haematology, University of the Witwatersrand, Johannesburg, South Africa. kcorin@gmail.com.
  • Skuhersky M; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, 90095-1570, USA. kcorin@gmail.com.
  • Vogel H; Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015, Lausanne, Switzerland.
  • Zhang S; Center for Bits and Atoms, Massachusetts Institute of Technology, Cambridge, MA, 02139-4307, USA.
Sci Rep ; 10(1): 21371, 2020 12 07.
Article en En | MEDLINE | ID: mdl-33288780

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores CXCR4 / Proteínas de la Membrana Límite: Humans Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores CXCR4 / Proteínas de la Membrana Límite: Humans Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido