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Evaluation of Muscle Cramp Associated with Liver Cirrhosis with a Focus on the Liver Function and Nutritional Status.
Shimada, Masaaki; Hirashima, Noboru; Iwase, Hiroaki; Saito, Masashi; Kondo, Hisashi; Urata, Noboru; Unita, Satoshi; Kondo, Takashi; Tanaka, Daiki; Tsunekawa, Takuya; Fujishiro, Mitsuhiro.
Afiliación
  • Shimada M; Department of Gastroenterology, National Hospital Organization, Nagoya Medical Center, Japan.
  • Hirashima N; Department of Gastroenterology, National Hospital Organization, Nagoya Medical Center, Japan.
  • Iwase H; Department of Gastroenterology, National Hospital Organization, Nagoya Medical Center, Japan.
  • Saito M; Department of Gastroenterology, National Hospital Organization, Nagoya Medical Center, Japan.
  • Kondo H; Department of Gastroenterology, National Hospital Organization, Nagoya Medical Center, Japan.
  • Urata N; Department of Gastroenterology, National Hospital Organization, Nagoya Medical Center, Japan.
  • Unita S; Department of Gastroenterology, National Hospital Organization, Nagoya Medical Center, Japan.
  • Kondo T; Department of Gastroenterology, National Hospital Organization, Nagoya Medical Center, Japan.
  • Tanaka D; Department of Gastroenterology, National Hospital Organization, Nagoya Medical Center, Japan.
  • Tsunekawa T; Department of Gastroenterology, National Hospital Organization, Nagoya Medical Center, Japan.
  • Fujishiro M; Department of Gastroenterology & Hepatology, Nagoya University Graduate School of Medicine, Japan.
Intern Med ; 60(9): 1343-1348, 2021 May 01.
Article en En | MEDLINE | ID: mdl-33281163
Objective We investigated the muscle cramp status of patients with liver cirrhosis by focusing on the degree of liver damage, skeletal muscle mass, and nutritional status. Methods All enrolled patients completed a questionnaire about muscle cramps. The degree of liver damage was examined using the Child-Pugh classification and the albumin-bilirubin (ALBI) grade. The nutritional status and skeletal muscle mass were examined using the Controlling Nutritional Status (CONUT) method and the psoas muscle index (PMI). Results Among the respondents, 55.7% of the patients reported experiencing muscle cramps. An analysis of the two patient groups-those who experienced muscle cramps and those who did not-revealed significant differences in Child-Pugh classification (muscle cramp-positive vs. muscle cramp-negative: A/B/C, 54.1%/32.4%/13.5% vs. 90.0%/10.0%/0.0%; p=0.004), ALBI grade (1/2/3, 20.5%/71.8%/7.7% vs. 54.8%/38.7%/6.5%; p=0.011), modified ALBI grade (1/2a/2b/3, 20.5%/20.5%/51.3%/7.7% vs. 54.8%/22.6%/16.1%/6.5%; p=0.008), CONUT score (normal/mild/moderate/severe, 25.6%/28.2%/41.0%/5.1% vs. 22.6%/61.3%/12.9%/3.2%; p=0.024), and PMI (3.85±1.13 cm2/m2 vs. 4.94±1.86 cm2/m2; p=0.012). Conclusion Our findings suggest that muscle cramps occur more frequently in patients with liver cirrhosis due to their decreased liver function and poorer nutritional status.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Hepáticas / Calambre Muscular Tipo de estudio: Diagnostic_studies / Etiology_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Hepáticas / Calambre Muscular Tipo de estudio: Diagnostic_studies / Etiology_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón