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Left atrial hypertension and the risk of early incident heart failure after atrial fibrillation ablation.
Gilge, Jasen L; Ahmed, Asim; Clark, Brad A; Slaten, Alexander; Devathu, Rahul; Olson, Jeffrey A; Padanilam, Benzy J; Nair, Girish V; Joshi, Sandeep A; Ravichandran, Ashwin K; Patel, Parin J.
Afiliación
  • Gilge JL; Division of Cardiology, Department of Internal Medicine, St. Vincent Medical Group, Indianapolis, Indiana, USA.
  • Ahmed A; Division of Cardiology, Department of Internal Medicine, St. Vincent Medical Group, Indianapolis, Indiana, USA.
  • Clark BA; Division of Cardiology, Department of Internal Medicine, St. Vincent Medical Group, Indianapolis, Indiana, USA.
  • Slaten A; Division of Cardiology, Department of Internal Medicine, St. Vincent Medical Group, Indianapolis, Indiana, USA.
  • Devathu R; Division of Cardiology, Department of Internal Medicine, St. Vincent Medical Group, Indianapolis, Indiana, USA.
  • Olson JA; Division of Cardiology, Department of Internal Medicine, St. Vincent Medical Group, Indianapolis, Indiana, USA.
  • Padanilam BJ; Division of Cardiology, Department of Internal Medicine, St. Vincent Medical Group, Indianapolis, Indiana, USA.
  • Nair GV; Division of Cardiology, Department of Internal Medicine, St. Vincent Medical Group, Indianapolis, Indiana, USA.
  • Joshi SA; Division of Cardiology, Department of Internal Medicine, St. Vincent Medical Group, Indianapolis, Indiana, USA.
  • Ravichandran AK; Division of Cardiology, Department of Internal Medicine, St. Vincent Medical Group, Indianapolis, Indiana, USA.
  • Patel PJ; Division of Cardiology, Department of Internal Medicine, St. Vincent Medical Group, Indianapolis, Indiana, USA.
J Cardiovasc Electrophysiol ; 32(2): 325-332, 2021 02.
Article en En | MEDLINE | ID: mdl-33270311
INTRODUCTION: Elevated left atrial pressure (LAP) during catheter ablation of atrial fibrillation (AF) is associated with an increased risk of AF recurrence, but it is unknown if this correlates with heart failure (HF). The objective of the study was to determine if elevated LAP after AF ablation correlates with HF events. METHODS: Prospective, single-center, cohort study measuring LAP and right atrial pressure (RAP) during AF ablation in 100 patients. The primary endpoint was clinical HF within 30 days of ablation. The secondary outcome was AF-free HF. RESULTS: One hundred patients (63% male, mean age 64.5) were enrolled and 20% had clinical HF within 30 days. Bivariate correlates included mitral valve (MV) disease, persistent AF, class III antiarrhythmics, LAP, and recurrent AF. Multivariate analysis revealed class III antiarrhythmics were protective (odds ratio [OR]: 0.24 [0.1-0.5], p = .04), while MV disease (OR: 8.7 [3.3-23], p = .03) and loop diuretics (OR: 4.8 [2.6-9.1], p = .01) were hazardous. AF-free HF occurred in 9% of patients and correlated with higher LAP and RAP, and chronic kidney disease. CONCLUSION: Patients with HF after AF ablation had higher LAP. MV disease, diuretic use, and class III antiarrhythmics also correlated to HF. These present opportunities to target future interventions to reduce a common complication of AF ablation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fibrilación Atrial / Ablación por Catéter / Insuficiencia Cardíaca / Hipertensión Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: J Cardiovasc Electrophysiol Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / FISIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fibrilación Atrial / Ablación por Catéter / Insuficiencia Cardíaca / Hipertensión Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: J Cardiovasc Electrophysiol Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / FISIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos