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Determinants of aflatoxin exposures in Kenyan School-aged children.
Wangia-Dixon, Ruth Nabwire; Quach, Trang Ho Thu; Song, Xiao; Ombaka, James; Githanga, David Peter; Anzala, Omu Aggrey; Wang, Jia-Sheng.
Afiliación
  • Wangia-Dixon RN; Department of Environmental Health Science, University of Georgia, Athens, USA.
  • Quach THT; KAVI Institute of Clinical Research, University of Nairobi, Nairobi, Kenya.
  • Song X; Faculty of Pharmacy, Ho Chi Minh City University of Technology (HUTECH), Vietnam.
  • Ombaka J; Department of Epidemiology and Biostatistics, University of Georgia, Athens, USA.
  • Githanga DP; Department of Epidemiology and Biostatistics, University of Georgia, Athens, USA.
  • Anzala OA; School of Public Health and Community Development, Maseno University, Maseno, Kenya.
  • Wang JS; Nairobi Hospital, Hospital Road, Nairobi, Kenya.
Int J Environ Health Res ; 32(6): 1183-1191, 2022 Jun.
Article en En | MEDLINE | ID: mdl-33256462
Aflatoxins are naturally occurring food toxins known to contaminate cereals with a carry-over effect in milk and meat products from farm animals raised on contaminated feed. In children, continuous consumption of aflatoxin-contaminated food is linked to immune suppression, vaccine interference and growth faltering while in adult populations, carcinogenesis in the liver has been established. We evaluate the main determinants of aflatoxin exposures among children recruited from primary schools in Makueni and Siaya Counties. A five-part questionnaire was administered to collect information from randomly selected participants. AflatoxinB1-lysine adducts in children's sera and total aflatoxins in food samples were analyzed by High-Performance Liquid Chromatography with Fluorescence detection. Using Chi-squared tests and Kruskal-Wallis tests, children from low-income households had the highest aflatoxin exposure, p-value = 0.0029. Smaller family size, greater food diversity, and good farming practices were associated with low aflatoxin exposures p < 0.001. Individual households living under severe levels of poverty were evidently exposed to higher levels of aflatoxins.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aflatoxinas Límite: Animals / Child / Humans País/Región como asunto: Africa Idioma: En Revista: Int J Environ Health Res Asunto de la revista: SAUDE AMBIENTAL Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aflatoxinas Límite: Animals / Child / Humans País/Región como asunto: Africa Idioma: En Revista: Int J Environ Health Res Asunto de la revista: SAUDE AMBIENTAL Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido