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Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-controlled clinical trial.
Vitale, Salvatore Giovanni; Corrado, Francesco; Caruso, Salvatore; Di Benedetto, Antonino; Giunta, Loretta; Cianci, Antonio; D'Anna, Rosario.
Afiliación
  • Vitale SG; Obstetrics and Gynecology Unit, Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
  • Corrado F; Department of Obstetrics and Gynecology, University of Messina, Messina, Italy.
  • Caruso S; Obstetrics and Gynecology Unit, Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
  • Di Benedetto A; Department of Internal Medicine, University of Messina, Messina, Italy.
  • Giunta L; Department of Internal Medicine, University of Messina, Messina, Italy.
  • Cianci A; Obstetrics and Gynecology Unit, Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
  • D'Anna R; Department of Obstetrics and Gynecology, University of Messina, Messina, Italy.
Int J Food Sci Nutr ; 72(5): 670-679, 2021 Aug.
Article en En | MEDLINE | ID: mdl-33238798
This study aims to evaluate the effects of myo-inositol supplementation on gestational diabetes mellitus (GDM) rates and body water distribution in overweight non-obese women. 223 overweight non-obese women pregnant were randomly assigned to the treatment group (2 g of myo-inositol plus 200 µg of folic acid) or to the placebo one (200 µg of folic acid). The treatment lasted until three weeks after delivery. A tetrapolar impedance analyser was used to study body composition. The incidence of GDM was significantly reduced in the myo-inositol group compared with the placebo group. There was a significant increase in TBW, ECW and ICW values in the placebo group compared to the myo-inositol group. We have recorded a significant reduction in the overall incidence of pregnancy-induced hypertension in the myo-inositol group compared with the placebo group. Our results demonstrate the effectiveness of myo-inositol supplementation in preventing GDM in overweight non-obese pregnant women.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Gestacional / Suplementos Dietéticos / Inositol Tipo de estudio: Clinical_trials Límite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: Int J Food Sci Nutr Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Gestacional / Suplementos Dietéticos / Inositol Tipo de estudio: Clinical_trials Límite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: Int J Food Sci Nutr Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido