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Oxidative stress mediates age-related hypertrophy of ligamentum flavum by inducing inflammation, fibrosis, and apoptosis through activating Akt and MAPK pathways.
Chuang, Hao-Chun; Tsai, Kun-Ling; Tsai, Kuen-Jer; Tu, Ting-Yuan; Shyong, Yan-Jye; Jou, I-Ming; Hsu, Che-Chia; Shih, Shu-Shien; Liu, Yuan-Fu; Lin, Cheng-Li.
Afiliación
  • Chuang HC; Department of Orthopaedic Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Tsai KL; Department of Physical Therapy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Tsai KJ; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Tu TY; Research Center of Clinical Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Shyong YJ; Department of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan.
  • Jou IM; Department of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, Tainan, Taiwan.
  • Hsu CC; Department of Orthopedics, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.
  • Shih SS; Department of Orthopaedic Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Liu YF; Department of Orthopaedic Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Lin CL; Department of Orthopaedic Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Aging (Albany NY) ; 12(23): 24168-24183, 2020 11 20.
Article en En | MEDLINE | ID: mdl-33223505
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estenosis Espinal / Apoptosis / Ligamento Amarillo / Estrés Oxidativo / Mediadores de Inflamación / Proteínas Quinasas Activadas por Mitógenos / Proteínas Proto-Oncogénicas c-akt / Desplazamiento del Disco Intervertebral Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Aging (Albany NY) Asunto de la revista: GERIATRIA Año: 2020 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estenosis Espinal / Apoptosis / Ligamento Amarillo / Estrés Oxidativo / Mediadores de Inflamación / Proteínas Quinasas Activadas por Mitógenos / Proteínas Proto-Oncogénicas c-akt / Desplazamiento del Disco Intervertebral Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Aging (Albany NY) Asunto de la revista: GERIATRIA Año: 2020 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Estados Unidos