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Safety Assessment of Trimellitic Anhydride Copolymers as Used in Cosmetics.
Fiume, Monice M; Bergfeld, Wilma F; Belsito, Donald V; Hill, Ronald A; Klaassen, Curtis D; Liebler, Daniel C; Marks, James G; Shank, Ronald C; Slaga, Thomas J; Snyder, Paul W; Gill, Lillian J; Heldreth, Bart.
Afiliación
  • Fiume MM; *44002Cosmetic Ingredient Review Senior Director.
  • Bergfeld WF; **Expert Panel for Cosmetic Ingredient Safety Member.
  • Belsito DV; **Expert Panel for Cosmetic Ingredient Safety Member.
  • Hill RA; **Expert Panel for Cosmetic Ingredient Safety Member.
  • Klaassen CD; **Expert Panel for Cosmetic Ingredient Safety Member.
  • Liebler DC; **Expert Panel for Cosmetic Ingredient Safety Member.
  • Marks JG; **Expert Panel for Cosmetic Ingredient Safety Member.
  • Shank RC; **Expert Panel for Cosmetic Ingredient Safety Member.
  • Slaga TJ; **Expert Panel for Cosmetic Ingredient Safety Member.
  • Snyder PW; **Expert Panel for Cosmetic Ingredient Safety Member.
  • Gill LJ; ***44002Cosmetic Ingredient Review Former Director.
  • Heldreth B; †44002Cosmetic Ingredient Review Executive Director.
Int J Toxicol ; 39(3_suppl): 74S-92S, 2020.
Article en En | MEDLINE | ID: mdl-33203270
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 6 trimellitic anhydride copolymers as used in cosmetics. These ingredients are related as copolymers in that they all share trimellitic anhydride (ie, 1,2,4-benzenetricarboxylic acid anhydride) as a monomer, are reported to function as film formers in cosmetics, and are reported to be primarily used in nail products. Very limited safety data were available or submitted. The Panel concluded that Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer and Phthalic Anhydride/Trimellitic Anhydride/Glycols Copolymer are safe in nail product formulations in the present practices of use and concentration, but the data are insufficient to make a determination of safety on the use of these 2 ingredients in all other types of cosmetic formulations. The Panel also concluded that the available data are insufficient to make a determination that the remaining trimellitic anhydride copolymers are safe for use in cosmetic formulations.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Anhídridos Ftálicos / Cosméticos Límite: Animals / Humans Idioma: En Revista: Int J Toxicol Asunto de la revista: TOXICOLOGIA Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Anhídridos Ftálicos / Cosméticos Límite: Animals / Humans Idioma: En Revista: Int J Toxicol Asunto de la revista: TOXICOLOGIA Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos