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Wild Isolates of Neurospora crassa Reveal Three Conidiophore Architectural Phenotypes.
Krach, Emily K; Wu, Yue; Skaro, Michael; Mao, Leidong; Arnold, Jonathan.
Afiliación
  • Krach EK; Genetics Department, University of Georgia, Athens, GA 30602, USA.
  • Wu Y; Institute of Bioinformatics, University of Georgia, Athens, GA 30602, USA.
  • Skaro M; Institute of Bioinformatics, University of Georgia, Athens, GA 30602, USA.
  • Mao L; School of Electrical and Computer Engineering, College of Engineering, University of Georgia, Athens, GA 30602, USA.
  • Arnold J; Genetics Department, University of Georgia, Athens, GA 30602, USA.
Microorganisms ; 8(11)2020 Nov 09.
Article en En | MEDLINE | ID: mdl-33182369
The vegetative life cycle in the model filamentous fungus, Neurospora crassa, relies on the development of conidiophores to produce new spores. Environmental, temporal, and genetic components of conidiophore development have been well characterized; however, little is known about their morphological variation. We explored conidiophore architectural variation in a natural population using a wild population collection of 21 strains from Louisiana, United States of America (USA). Our work reveals three novel architectural phenotypes, Wild Type, Bulky, and Wrap, and shows their maintenance throughout the duration of conidiophore development. Furthermore, we present a novel image-classifier using a convolutional neural network specifically developed to assign conidiophore architectural phenotypes in a high-throughput manner. To estimate an inheritance model for this discrete complex trait, crosses between strains of each phenotype were conducted, and conidiophores of subsequent progeny were characterized using the trained classifier. Our model suggests that conidiophore architecture is controlled by at least two genes and has a heritability of 0.23. Additionally, we quantified the number of conidia produced by each conidiophore type and their dispersion distance, suggesting that conidiophore architectural phenotype may impact N. crassa colonization capacity.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Microorganisms Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Microorganisms Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza