CRISPR/Cas9 mediated establishment of a human CSRP3 compound heterozygous knockout hESC line to model cardiomyopathy and heart failure.

Sun, Liqiang; Li, Jing; Li, En; Niu, Shaohui; Qin, Zhiping; Zhi, Qing; Zhao, Jiajia; Xiong, Haiyan; Li, Yuan; Jian, Liguo; Zhang, Lihua

Sun, Liqiang; Li, Jing; Li, En; Niu, Shaohui; Qin, Zhiping; Zhi, Qing; Zhao, Jiajia; Xiong, Haiyan; Li, Yuan; Jian, Liguo; Zhang, Lihua.

Afiliación

Sun L; Department of Cardiology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Li J; Department of Nuclear Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Li E; Department of Cardiology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Niu S; Department of Cardiology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Qin Z; Department of Doppler Ultrasonic, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Zhi Q; Department of Cardiology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Zhao J; Department of Cardiology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Xiong H; Department of Cardiology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Li Y; Department of Cardiology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Jian L; Department of Cardiology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. Electronic address: jlg0919@163.com.
Zhang L; Department of Cardiology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. Electronic address: zlhxp@126.com.

Stem Cell Res ; 49: 102077, 2020 12.

Article en En | MEDLINE | ID: mdl-33176267

Asunto(s)

Cardiomiopatías; Insuficiencia Cardíaca; Células Madre Embrionarias Humanas; Sistemas CRISPR-Cas/genética; Cardiomiopatías/genética; Línea Celular; Femenino; Insuficiencia Cardíaca/genética; Humanos

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Embrionarias Humanas / Insuficiencia Cardíaca / Cardiomiopatías Límite: Female / Humans Idioma: En Revista: Stem Cell Res Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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