INDEL detection, the 'Achilles heel' of precise genome editing: a survey of methods for accurate profiling of gene editing induced indels.

Bennett, Eric Paul; Petersen, Bent Larsen; Johansen, Ida Elisabeth; Niu, Yiyuan; Yang, Zhang; Chamberlain, Christopher Aled; Met, Özcan; Wandall, Hans H; Frödin, Morten

Bennett, Eric Paul; Petersen, Bent Larsen; Johansen, Ida Elisabeth; Niu, Yiyuan; Yang, Zhang; Chamberlain, Christopher Aled; Met, Özcan; Wandall, Hans H; Frödin, Morten.

Afiliación

Bennett EP; Copenhagen Center for Glycomics, Department of Odontology and Molecular and Cellular Medicine, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Petersen BL; Department of Plant and Environmental Sciences, University of Copenhagen, DK-1871 Frederiksberg C, Denmark.
Johansen IE; Department of Plant and Environmental Sciences, University of Copenhagen, DK-1871 Frederiksberg C, Denmark.
Niu Y; Biotech Research and Innovation Centre (BRIC), Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
Yang Z; College of Animal Science and Technology, Northwest A&F University, Yangling Shaanxi, China.
Chamberlain CA; Copenhagen Center for Glycomics, Department of Odontology and Molecular and Cellular Medicine, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Met Ö; Center for Cancer Immune Therapy, Department of Oncology, Copenhagen University Hospital, Herlev, Denmark.
Wandall HH; Center for Cancer Immune Therapy, Department of Oncology, Copenhagen University Hospital, Herlev, Denmark.
Frödin M; Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Nucleic Acids Res ; 48(21): 11958-11981, 2020 12 02.

Article en En | MEDLINE | ID: mdl-33170255

Asunto(s)

Sistemas CRISPR-Cas; Reparación del ADN; ADN/genética; Edición Génica/métodos; Genoma; Mutación INDEL; Animales; Clonación de Organismos/métodos; ADN/metabolismo; Roturas del ADN de Doble Cadena; Reparación del ADN por Unión de Extremidades; Técnicas de Inactivación de Genes; Humanos; Ratones; Ovinos/genética; Solanum tuberosum/genética; Nucleasas de los Efectores Tipo Activadores de la Transcripción/genética; Nucleasas de los Efectores Tipo Activadores de la Transcripción/metabolismo; Nucleasas con Dedos de Zinc/genética; Nucleasas con Dedos de Zinc/metabolismo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN / Genoma / Reparación del ADN / Mutación INDEL / Sistemas CRISPR-Cas / Edición Génica Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Año: 2020 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido

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