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Targeting TOPK sensitises tumour cells to radiation-induced damage by enhancing replication stress.
Herbert, Katharine J; Puliyadi, Rathi; Prevo, Remko; Rodriguez-Berriguete, Gonzalo; Ryan, Anderson; Ramadan, Kristijan; Higgins, Geoff S.
Afiliación
  • Herbert KJ; MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Puliyadi R; MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Prevo R; MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Rodriguez-Berriguete G; MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Ryan A; MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Ramadan K; MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Higgins GS; MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK. geoffrey.higgins@oncology.ox.ac.uk.
Cell Death Differ ; 28(4): 1333-1346, 2021 04.
Article en En | MEDLINE | ID: mdl-33168956
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tolerancia a Radiación / Fosfatasas cdc25 / Quinasas de Proteína Quinasa Activadas por Mitógenos / Quinasa 1 Reguladora del Ciclo Celular (Checkpoint 1) / Neoplasias Pulmonares Límite: Animals / Female / Humans Idioma: En Revista: Cell Death Differ Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tolerancia a Radiación / Fosfatasas cdc25 / Quinasas de Proteína Quinasa Activadas por Mitógenos / Quinasa 1 Reguladora del Ciclo Celular (Checkpoint 1) / Neoplasias Pulmonares Límite: Animals / Female / Humans Idioma: En Revista: Cell Death Differ Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido