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In-hospital outcomes of COVID-19 ST-elevation myocardial infarction patients.
EuroIntervention ; 16(17): 1426-1433, 2021 04 20.
Article en En | MEDLINE | ID: mdl-33164893
AIMS: The aim of this study was to assess clinical and prognosis differences in patients with COVID-19 and STEMI. METHODS AND RESULTS: Using a nationwide registry of consecutive patients managed within 42 specific STEMI care networks, we compared patient and procedure characteristics and in-hospital outcomes in two different cohorts, according to whether or not they had COVID-19. Among 1,010 consecutive STEMI patients, 91 were identified as having COVID-19 (9.0%). With the exception of smoking status (more frequent in non-COVID-19 patients) and previous coronary artery disease (more frequent in COVID-19 patients), clinical characteristics were similar between the groups, but COVID-19 patients had more heart failure on arrival (31.9% vs 18.4%, p=0.002). Mechanical thrombectomy (44% vs 33.5%, p=0.046) and GP IIb/IIIa inhibitor administration (20.9% vs 11.2%, p=0.007) were more frequent in COVID-19 patients, who had an increased in-hospital mortality (23.1% vs 5.7%, p<0.0001), that remained consistent after adjustment for age, sex, Killip class and ischaemic time (OR 4.85, 95% CI: 2.04-11.51; p<0.001). COVID-19 patients had an increase of stent thrombosis (3.3% vs 0.8%, p=0.020) and cardiogenic shock development after PCI (9.9% vs 3.8%, p=0.007). CONCLUSIONS: Our study revealed a significant increase in in-hospital mortality, stent thrombosis and cardiogenic shock development after PCI in patients with STEMI and COVID-19 in comparison with contemporaneous non-COVID-19 STEMI patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Intervención Coronaria Percutánea / Infarto del Miocardio con Elevación del ST / COVID-19 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: EuroIntervention Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / TERAPEUTICA Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Francia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Intervención Coronaria Percutánea / Infarto del Miocardio con Elevación del ST / COVID-19 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: EuroIntervention Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / TERAPEUTICA Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Francia