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Risk factors for predicting cement leakage in percutaneous vertebroplasty for spinal metastases.
Cui, Yunpeng; Pan, Yuanxing; Lin, Yunfei; Mi, Chuan; Wang, Bing; Shi, Xuedong.
Afiliación
  • Cui Y; Department of Orthopaedics, Peking University First Hospital, Beijing, China.
  • Pan Y; Department of Orthopaedics, Peking University First Hospital, Beijing, China.
  • Lin Y; Department of Orthopaedics, Peking University First Hospital, Beijing, China.
  • Mi C; Department of Orthopaedics, Peking University First Hospital, Beijing, China.
  • Wang B; Department of Orthopaedics, Peking University First Hospital, Beijing, China.
  • Shi X; Department of Orthopaedics, Peking University First Hospital, Beijing, China. Electronic address: pku_ortho@163.com.
J Orthop Sci ; 27(1): 79-83, 2022 Jan.
Article en En | MEDLINE | ID: mdl-33158733
BACKGROUND: The study aimed to identify the risk factors of cement leakage following percutaneous vertebroplasty for spinal metastases. METHODS: 230 consecutive patients with 530 vertebrae were retrospectively reviewed. Characteristics including age, primary cancer, location, pathological fracture, the integrity of the posterior wall, and the volume of bone cement were considered as potential risk factors. Cement leakage was evaluated by postoperative imaging examination and classified into three subtypes with different potential sequelae: spinal canal leakage, intravascular leakage around vertebrae, intradiscal and paravertebral leakage. Univariate and multivariate analyses were used to assess the risk factors. RESULTS: Leakage was detected in 185 vertebrae (34.9%), 18.3% for intradiscal and paravertebral, 13.2% for intravascular around vertebrae, and 7.0% for spinal canal. Multivariate analysis showed that incomplete posterior wall (P = 0.001) and breast cancer (P = 0.015) were strong predictive factors for spinal canal leakage, incomplete posterior wall (P = 0.024) was for intravascular leakage around vertebrae, thoracic (P = 0.010) and pathological fracture (P = 0.000) were for intradiscal and paravertebral leakage. CONCLUSIONS: Our findings suggest that cement leakage is common following percutaneous vertebroplasty for spinal metastases. The incomplete posterior wall is an unfavourable factor for intravascular leakage around vertebrae. Vertebrae with incomplete posterior wall and breast cancer metastases are more likely to develop spinal canal leakage.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Columna Vertebral / Fracturas de la Columna Vertebral / Fracturas por Compresión / Vertebroplastia Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Orthop Sci Asunto de la revista: ORTOPEDIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Columna Vertebral / Fracturas de la Columna Vertebral / Fracturas por Compresión / Vertebroplastia Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Orthop Sci Asunto de la revista: ORTOPEDIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Japón