Matrilysins and Stromelysins in Pathogenesis and Diagnostics of Cancers.
Cancer Manag Res
; 12: 10949-10964, 2020.
Article
en En
| MEDLINE
| ID: mdl-33154674
Matrix metalloproteinases (MMPs) are endopeptidases which are widely studied in terms of their role in the physiological and pathological processes in the organism. In this article, we consider usefulness of matrilysins and stromelysins in pathogenesis and diagnostic of the most common malignancies in the world, e.g., lung, breast, prostate, and colorectal cancers. In all of the mentioned cancers, matrilysins and stromelysins have a pivotal role in their development and also may have diagnostic utility. Influence to the cancerous process is connected with specific dependencies between these enzymes and components of the extracellular matrix (ECM), non-matrix components like cell surface components. All the information provided below allows to take a closer look at matrilysins and stromelysins and their functions in the cancer development.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
Idioma:
En
Revista:
Cancer Manag Res
Año:
2020
Tipo del documento:
Article
País de afiliación:
Polonia
Pais de publicación:
Nueva Zelanda