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Matrilysins and Stromelysins in Pathogenesis and Diagnostics of Cancers.
Piskór, Barbara Maria; Przylipiak, Andrzej; Dabrowska, Emilia; Niczyporuk, Marek; Lawicki, Slawomir.
Afiliación
  • Piskór BM; Department of Aesthetic Medicine, Medical University of Bialystok, Bialystok, Poland.
  • Przylipiak A; Department of Aesthetic Medicine, Medical University of Bialystok, Bialystok, Poland.
  • Dabrowska E; Department of Aesthetic Medicine, Medical University of Bialystok, Bialystok, Poland.
  • Niczyporuk M; Department of Aesthetic Medicine, Medical University of Bialystok, Bialystok, Poland.
  • Lawicki S; Department of Population Medicine and Civilization Diseases Prevention, Medical University of Bialystok, Bialystok, Poland.
Cancer Manag Res ; 12: 10949-10964, 2020.
Article en En | MEDLINE | ID: mdl-33154674
Matrix metalloproteinases (MMPs) are endopeptidases which are widely studied in terms of their role in the physiological and pathological processes in the organism. In this article, we consider usefulness of matrilysins and stromelysins in pathogenesis and diagnostic of the most common malignancies in the world, e.g., lung, breast, prostate, and colorectal cancers. In all of the mentioned cancers, matrilysins and stromelysins have a pivotal role in their development and also may have diagnostic utility. Influence to the cancerous process is connected with specific dependencies between these enzymes and components of the extracellular matrix (ECM), non-matrix components like cell surface components. All the information provided below allows to take a closer look at matrilysins and stromelysins and their functions in the cancer development.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Etiology_studies Idioma: En Revista: Cancer Manag Res Año: 2020 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Nueva Zelanda

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Etiology_studies Idioma: En Revista: Cancer Manag Res Año: 2020 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Nueva Zelanda