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Novel sex-specific influence of parental factors on small-for-gestational-age newborns.
Tian, Meng Yuan; Wen, Shi Wu; Retnakaran, Ravi; Wang, Hao Ren; Ma, Shu Juan; Chen, Meng Shi; Wang, Xiao Lei; Lin, Hui Jun; Tan, Hong Zhuan.
Afiliación
  • Tian MY; Xiangya School of Public Health, Central South University, Changsha, China.
  • Wen SW; OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, ON, Canada.
  • Retnakaran R; Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Wang HR; Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, ON, Canada.
  • Ma SJ; Division of Endocrinology, University of Toronto, Toronto, ON, Canada.
  • Chen MS; Xiangya School of Public Health, Central South University, Changsha, China.
  • Wang XL; Xiangya School of Public Health, Central South University, Changsha, China.
  • Lin HJ; Xiangya School of Public Health, Central South University, Changsha, China.
  • Tan HZ; Xiangya School of Public Health, Central South University, Changsha, China.
Sci Rep ; 10(1): 19226, 2020 11 05.
Article en En | MEDLINE | ID: mdl-33154528
Since fetal programming is sex-specific, there may also be sex-specific in parental influences on newborn birth weight. We aimed to investigate the influence of parental factors on small-for-gestational-age (SGA) infants of different sexes. Based on a pre-pregnancy cohort, multivariate logistic regression was used. 2275 couples were included for analysis. Significant associations were observed among paternal height, pre-pregnancy body mass index (BMI), and SGA in male infants; among maternal height, pre-pregnancy BMI, and SGA in female infants, and among other maternal factors and SGA in both male and female infants. Such sex specificity may be related to genetic, epigenetic, or hormonal influences between parents and infants. In conclusion, there is a sex specificity in the effect of parental height and pre-pregnancy BMI on SGA. The data suggest that future studies on infants should consider the sex-specific differences between the effects of genetic or environmental factors and infants.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Padres / Peso al Nacer / Estatura / Recién Nacido Pequeño para la Edad Gestacional / Índice de Masa Corporal / Desarrollo Fetal Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Newborn / Pregnancy Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Padres / Peso al Nacer / Estatura / Recién Nacido Pequeño para la Edad Gestacional / Índice de Masa Corporal / Desarrollo Fetal Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Newborn / Pregnancy Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido