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Characteristics and outcomes of critically ill patients with influenza A (H1N1) in the Western Balkans during the 2019 post-pandemic season.
Kovacevic, Pedja; Matijasevic, Jovan; Dragic, Sasa; Zlojutro, Biljana; Gavrilovic, Srdjan; Jandric, Milka; Andrijevic, Ana; Kovacevic, Tijana; Carapic, Vladimir; Travar, Maja; Preradovic, Ljubisa; Momcicevic, Danica.
Afiliación
  • Kovacevic P; Medical Intensive Care Unit, University Clinical Center of Republika Srpska; Faculty of Medicine, University of Banja Luka, Bosnia and Herzegovina, Novi Sad, Serbia.
  • Matijasevic J; Institute for Pulmonary Diseases, Medical School University of Novi Sad, Novi Sad, Serbia.
  • Dragic S; Medical Intensive Care Unit, University Clinical Center of Republika Srpska, Novi Sad, Serbia.
  • Zlojutro B; Medical Intensive Care Unit, University Clinical Center of Republika Srpska, Novi Sad, Serbia.
  • Gavrilovic S; Institute for Pulmonary Diseases, Medical School University of Novi Sad, Novi Sad, Serbia.
  • Jandric M; Medical Intensive Care Unit, University Clinical Center of Republika Srpska, Novi Sad, Serbia.
  • Andrijevic A; Institute for Pulmonary Diseases, Medical School University of Novi Sad, Novi Sad, Serbia.
  • Kovacevic T; Faculty of Medicine, University of Banja Luka, Bosnia and Herzegovina; Department of Pharmacy, University Clinical Center of Republika Srpska, Novi Sad, Serbia.
  • Carapic V; Institute for Pulmonary Diseases, Medical School University of Novi Sad, Novi Sad, Serbia.
  • Travar M; Faculty of Medicine, University of Banja Luka, Bosnia and Herzegovina; Department of Microbiology, University Clinical Center of Republika Srpska, Novi Sad, Serbia.
  • Preradovic L; Faculty of Medicine, University of Banja Luka, Bosnia and Herzegovina, Novi Sad, Serbia.
  • Momcicevic D; Medical Intensive Care Unit, University Clinical Center of Republika Srpska, Novi Sad, Serbia.
Indian J Med Microbiol ; 38(3 & 4): 415-420, 2020.
Article en En | MEDLINE | ID: mdl-33154256
Background: This study looked at the characteristics and outcomes of critically ill patients with confirmed influenza A (H1N1) pdm09 infection in the Western Balkans in the post-pandemic period. Materials and Methods: This retrospective observational study of medical records and associated data collected during the post-pandemic period included all mechanically ventilated adult patients of two university-affiliated hospitals of the Western Balkans between 1 January and 31 March 2019 who had influenza A (H1N1) pdm09 infection confirmed by real-time reverse transcriptase-polymerase chain reaction from nasopharyngeal swab specimens and respiratory secretions. Results: The study included 89 patients, 49 males (55.1%), aged 56.09 ± 12.64 years. The median time from shift from hospital time to intensive care unit was 1 day (range: 1-2). In the post-pandemic period, cases observed in this study were found to have the following comorbidities: cardiovascular diseases in 44 (49.4%) patients and diabetes in 21 (23.6%) patients. Thirty-one patients (34.8%) in this study were obese. All 89 patients (100%) experienced some degree of acute respiratory distress syndrome, and 39 (44%) had multiorgan failure. Eighty-three patients (93%) were intubated and mechanically ventilated, 6 (7%) received non-invasive mechanical ventilation, 12 (13%) were treated with vvECMO and 36 (40%) received renal replacement therapy. Vasoactive support was needed by 56 (63%) patients. The median duration of mechanical ventilation was 9 (6-15.5) days. The hospital mortality rate was 44%. Conclusion: Critically ill patients with confirmed influenza A (H1N1) pdm09 infection in the post-pandemic season were older, required vasoactive drugs more often, and there was a trend of higher survival compared to H1N1 infection patients in the previous pandemic seasons.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Dificultad Respiratoria / Enfermedades Cardiovasculares / Complicaciones de la Diabetes / Gripe Humana / Subtipo H1N1 del Virus de la Influenza A / Obesidad Tipo de estudio: Observational_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Indian J Med Microbiol Asunto de la revista: MICROBIOLOGIA Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Dificultad Respiratoria / Enfermedades Cardiovasculares / Complicaciones de la Diabetes / Gripe Humana / Subtipo H1N1 del Virus de la Influenza A / Obesidad Tipo de estudio: Observational_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Indian J Med Microbiol Asunto de la revista: MICROBIOLOGIA Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos