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Evaluating the Benefits of Exercise Training in HFrEF or COPD Patients: ISO-LEVEL COMPARISON CAN ADD VALUABLE INFORMATION TO V˙o2peak.
Gudjonsdottir, Marta; Thoroddsen, Egill; Karlsdottir, Arna E; Kristjansdottir, Asdis; Jonasson, Magnus R; Asgeirsdottir, Magdalena; Sigurdsson, Stefan B; Kristjansson, Karl.
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  • Gudjonsdottir M; Department of Physiology, University of Iceland, Reykjavík, Iceland (Dr Gudjonsdottir and Ms Thoroddsen); Cardiopulmonary Laboratory (Dr Gudjonsdottir and Ms Karlsdottir), Department of Pulmonary Rehabilitation (Ms Kristjansdottir and Dr Asgeirsdottir), and Department of Cardiac Rehabilitation (Drs Jonasson and Kristjansson), Reykjalundur Rehabilitation Centre, Reykjavík, Iceland; MS Iceland Dairies, Akureyri, Iceland (Ms Thoroddsen); and School of Health Sciences, University of Akureyri, Akurey
J Cardiopulm Rehabil Prev ; 40(6): 421-426, 2020 11.
Article en En | MEDLINE | ID: mdl-33148990
BACKGROUND: Heart failure with reduced ejection fraction (HFrEF) and chronic obstructive pulmonary disease (COPD) are relatively common conditions with similar symptoms of exercise intolerance and dyspnea. The aim of this study was to compare exercise capacity, ventilatory response, and breathing pattern in patient groups with either advanced HFrEF or COPD before and after exercise training. METHODS: An observational study was conducted with parallel groups of 25 HFrEF and 25 COPD patients who took part in 6 wk of inpatient rehabilitation with exercise training. All patients underwent cardiopulmonary exercise tests at the start and end of the training, with resting arterial blood gas measurements. RESULTS: The average peak oxygen uptake (V˙o2) was low at the start of the study but increased significantly after training in both groups, or by 2.2 ± 2.1 mL/kg/min in HFrEF patients and 1.2 ± 2.2 mL/kg/min in COPD patients. At ISO-V˙o2 (ie, same level of V˙o2 in pre- and post-exercise tests), carbon dioxide production (V˙co2) decreased after exercise training in both groups. Similarly, at ISO-V˙E (ie, same level of ventilation), breathing frequency (f) decreased and tidal volume (VT) increased, resulting in an improved breathing pattern (lower f/VT ratio) after training. CONCLUSION: The findings of this study show that exercise training in severely affected patient groups with HFrEF or COPD led to an increase in maximal exercise capacity, a more favorable breathing pattern, and a diminished V˙co2 during exercise. Therefore, comparisons of V˙co2 and breathing pattern at ISO-levels of V˙o2 or V˙E before and after training are valuable and underutilized outcome measures in treatment studies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad Pulmonar Obstructiva Crónica / Insuficiencia Cardíaca Tipo de estudio: Observational_studies Límite: Humans Idioma: En Revista: J Cardiopulm Rehabil Prev Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad Pulmonar Obstructiva Crónica / Insuficiencia Cardíaca Tipo de estudio: Observational_studies Límite: Humans Idioma: En Revista: J Cardiopulm Rehabil Prev Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos