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Recharge and increase in hardness of GIC with CPP-ACP/F.
Shen, Peiyan; Zalizniak, Ilya; Palamara, Joseph E A; Burrow, Michael F; Walker, Glenn D; Yuan, Yi; Reynolds, Coralie; Fernando, James R; Reynolds, Eric C.
Afiliación
  • Shen P; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria 3010, Australia.
  • Zalizniak I; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria 3010, Australia.
  • Palamara JEA; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria 3010, Australia.
  • Burrow MF; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria 3010, Australia.
  • Walker GD; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria 3010, Australia.
  • Yuan Y; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria 3010, Australia.
  • Reynolds C; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria 3010, Australia.
  • Fernando JR; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria 3010, Australia.
  • Reynolds EC; Oral Health Cooperative Research Centre, Melbourne Dental School, Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria 3010, Australia. Electronic address: e.reynolds@unimelb.edu.au.
Dent Mater ; 36(12): 1608-1614, 2020 12.
Article en En | MEDLINE | ID: mdl-33143938
OBJECTIVE: To assess the effect of CPP-ACP/F recharging on ion release and hardness of GIC Fuji-Triage (VII) and Fuji-Triage-EP (VII-EP) containing CPP-ACP/F. METHODS: CPP-ACP distribution in Fuji-Triage-EP was determined using immunofluorescence. Thirty blocks of Fuji-Triage and Fuji-Triage-EP with the same surface area were placed individually in 5mL of 50mM lactic acid (pH 5) for three days. Every 12h ten Fuji-Triage and ten Fuji-Triage-EP blocks were treated with 2mL of either MI Paste Plus (CPP-ACP/F) solution (1g paste+4mL water), Placebo MI paste solution (no CPP-ACP/F), or distilled water for 2min. After each 2min treatment the blocks were rinsed with distilled water and placed back into the acid. Calcium, inorganic phosphate and fluoride levels in the acid solution were measured using atomic absorption spectrophotometry, colorimetry and ion specific electrode respectively. Vickers surface hardness of the GIC was also determined. Data were analysed using a two-sample t-test and one-way ANOVA with a Bonferroni-Holm correction for multiple comparisons. RESULTS: CPP-ACP was distributed throughout Fuji-Triage-EP. Significantly (p<0.001) higher calcium, inorganic phosphate and fluoride ion release and greater surface hardness (acid resistance) was observed in both GIC's treated with the CPP-ACP/F paste. Fuji-Triage-EP released higher ion levels and exhibited greater surface hardness (acid resistance) than Fuji-Triage. SIGNIFICANCE: Topical application of CPP-ACP/F paste to GIC Fuji-Triage-EP recharged ion release and increased surface hardness (acid resistance) which may help improve properties and resistance to degradation as well as improve ion release for caries control.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esmalte Dental / Fluoruros Tipo de estudio: Clinical_trials Idioma: En Revista: Dent Mater Asunto de la revista: ODONTOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esmalte Dental / Fluoruros Tipo de estudio: Clinical_trials Idioma: En Revista: Dent Mater Asunto de la revista: ODONTOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido