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Fetal and Placental Weight in Pre-Gestational Maternal Obesity (PGMO) vs. Excessive Gestational Weight Gain (EGWG)-A Preliminary Approach to the Perinatal Outcomes in Diet-Controlled Gestational Diabetes Mellitus.
Gujski, Mariusz; Szukiewicz, Dariusz; Choluj, Marta; Sawicki, Wlodzimierz; Bojar, Iwona.
Afiliación
  • Gujski M; Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, 02-091 Warsaw, Poland.
  • Szukiewicz D; Chair and Department of General and Experimental Pathology with Centre for Preclinical Research and Technology, Medical University of Warsaw, ul. Pawinskiego 3C, 02-106 Warsaw, Poland.
  • Choluj M; Chair and Department of Obstetrics, Gynecology and Oncology, Medical University of Warsaw, 03-242 Warsaw, Poland.
  • Sawicki W; Chair and Department of Obstetrics, Gynecology and Oncology, Medical University of Warsaw, 03-242 Warsaw, Poland.
  • Bojar I; Department of Women's Health, Institute of Rural Health in Lublin, 20-950 Lublin, Poland.
J Clin Med ; 9(11)2020 Oct 31.
Article en En | MEDLINE | ID: mdl-33142800
Both pre-gestational maternal obesity (PGMO) and excessive gestational weight gain (EGWG) increase the risk of gestational diabetes mellitus (GDM). Here, we conducted a retrospective study to comparatively examine the relation between fetal birth weight (FW) and placental weight (PW) in PGMO (n = 100) compared to EGWG (n = 100) with respect to perinatal outcomes in diet-controlled GDM. The control group was made up of 100 healthy pregnancies. The mean FW and the mean PW in EGWG were correlated with lowered fetal weight/placental weight ratio (FW/PW ratio). The percentage of births completed by cesarean section accounted for 47%, 32%, and 18% of all deliveries (EGWG, PGMO, and controls, respectively), with the predominance of FW-related indications for cesarean section. Extended postpartum hospital stays due to neonate were more frequent in EGWG, especially due to neonatal jaundice (p < 0.05). The results indicate the higher perinatal risk in mothers with EGWG compared to PGMO during GDM-complicated pregnancy. Further in-depth comparative studies involving larger patient pools are needed to validate these findings, the intent of which is to formulate guidelines for GDM patients in respect to management of PGMO and EGWG.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: J Clin Med Año: 2020 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: J Clin Med Año: 2020 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Suiza